Reaction of cellular thiols with the 1,2-dithiolan-3-one 1-oxide moiety of leinamycin triggers the generation of DNA-damaging reactive intermediates. Studies with small, synthetic analogues of leinamycin reveal that the macrocyclic portion of the natural product imparts remarkable hydrolytic stability to the 1,2-dithiolan-3-one 1-oxide heterocycle without substantially compromising its thiol-se...

Introduction. Price is the main factor that has a direct impact on results of enter­prises, especially agricultural. The pricing policy able to maintain competitiveness enter­prise, ensure its solvency and stability. Problem. Pricing carried out in complex interaction set internal external Factors. corresponding complexity phenomenon leads need include many Factors model, which can negatively a...

The purpose of the research was to identify factors impelling buyers' attitude towards purchasing intention counterfeit products among customers. conceptual framework is proposed by different studies. All measures used were evaluated in terms their internal consistency also discriminant validity and convergent validate data questionnaire. A survey carried out on Oman market with 350 respondents...

The prevalence of Escherichia coli carrying resistance factors (R factors) was examined in meat-consuming individuals and in those not consuming meat (vegetarians and babies below the age of 6 months). Assuming that the transport of resistant E. coli from animals through meat and meat products to the human consumer is most important, with regard to the incidence of resistant E. coli in man, we ...

Among processed and manufactured dairy products marketed in the United States, yogurt has one of the shortest histories and sharpest growth trends. To examine the socioeconomic factors associated with U.S. at-home yogurt demand, a demand system is used to analyze three yogurt products. Findings suggest that own-prices have negative effects and total expenditure has a positive effect on U.S. yog...