Background: Controversial data concerning the elevation of serum angiotensin-converting enzyme in psoriasis are reported in the literature. In order to verify whether this abnormality exists in Iranian patients, we performed this study. Method: Serum angiotensin-converting enzyme level was measured in 40 psoriatics. According to clinical forms of psoriasis, patients were further divided into th...

background: the aim of this study was to determine the th1 and th2 serum cytokines, in patients with psoriasis and to com pare their cytokine levels with those of normal control subjects. methods: serum levels of interferon-gamma (ifn-γ), interleukin-2 (il-2), interleukin-4 (il-4), and interleukin-10 (il-10) were measured by enzyme linked immunosorbent assay in 40 patients with psoriasis and in...

background & objectives:  accurate differentiation of eczema and psoriasis can be difficult, especially in areas of palm and sole. this study was designed to evaluate histopathological features and identify statistically significant parameters in distinguishing palmoplantar psoriasis from eczema of these regions in patients referring to razi skin hospital, tehran, iran. methods: in a cross-...

Psoriasis is a common chronic inflammatory skin disease. The most common form of psoriasis is characterized by sharply demarcated, scaly, erythematous plaques. The face is an unusual site for psoriasis. Herein, we report a 43-year-old woman with facial psoriasis that was developed after remission–induction chemotherapy for acute leukemia with high dose cytarabine/daunorubicin.

Background: Adalimumab is a highly human monoclonal antibody that binds to tumor necrosis factor, a key proinflammatory cytokine pathogenic in psoriasis. It considers an influential factor in controlling moderate to severe psoriasis. This study aimed to evaluate the impact of Adalimumab on COVID-19 incidence in patients with psoriasis. Methods: This cross-sectional study was performed at Baqiy...

conclusions it is essential to identify people with psoriasis. another important point is to inform patients of the causes of this disease to decrease the risk of recurrence. in addition, it is recommended to educate patients about reduction or cessation of smoking as a part of psoriasis treatment. results the results of this study indicated that infection, stress, family history, blood calcium...

the goal of this study was to compare depression and quality of life in three auto immune diseases: psoriasis, vitiligo, and alopecia areata. from january 2009 until january 2010, 300 patients (100 with alopecia areata, 100 with psoriasis and 100 with vitiligo) who were randomly selected (by simple random selection) from outpatient clinic of razi hospital (center of skin diseases of tehran univ...

we present here a 32-year-old male with advanced lately diagnosed, right sided retroperitoneal mass, which had been already treated due to progressive muco-cutaneous lesions clinically consistent with psoriasis, during recent four years. the advanced retroperitoneal mass resected surgically and reported as hyaline-vascular castleman disease with a dense focus of coarse calcification, on histopa...

introduction:   palmoplantar psoriasis could hardly be differentiated from chronic tylotic eczema both clinically and histologically. the most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local puva. frequently, it is a recalcitrant disease. we investigated the efficacy and tolerability of the combination of topical calcipot...