نتایج جستجو برای: radiation lethality

تعداد نتایج: 248735  

Journal: :Applied and environmental microbiology 1985
J Avalos J Casadesús E Cerdá-Olmedo

N-methyl-N'-nitro-N-nitrosoguanidine (nitrosoguanidine) and to a lesser extent UV radiation are very mutagenic for Gibberella microconidia. The recommended nitrosoguanidine doses lead to much higher frequencies of mutants than are found in other microorganisms. The frequency of mutants among the survivors increases linearly with the nitrosoguanidine dose (molar concentration X time); the absolu...

2012
RONALD E. GOANS

INTRODUCTION PATHOPHYSIOLOGY Hematopoietic Syndrome Gastrointestinal Syndrome Neurovascular Syndrome DETERMINANTS OF RADIATION EFFECTS ON HUMANS Lethality Curve Influence of Trauma on LD50 Effect of Clinical Support on the LD50 Dose Effect Curve CLINICAL ASPECTS OF THE US CRITICALITY EXPERIENCE Clinical Course of the Criticality Cases CURRENT TREATMENT OF ACUTE RADIATION SYNDROME Supportive Car...

Journal: :Molecular & Cellular Toxicology 2022

Abstract Background Cranial radiation therapy for treating childhood malignancies in the central nervous system or accidental exposure may result neurological side effects surviving adults. As tissue homeostasis is maintained by stem cells, understanding effect of on neural cells will provide clues managing effects. Drosophila embryos were used as a model whose sensitivity to irradiation-induce...

Introduction It has long been known that ionizing radiation can lead to detrimental effects in normal cells. In this light, Radioprotective chemicals have been used to decrease morbidity or mortality caused by ionizing irradiation. This study aimed to evaluate the radio-protective effect of N-acetylcysteineagainst radiation-induced mortality in male mice. Materials and Methods 52 healthy mal...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Kwanghee Kim Julianne M Pollard Andrew J Norris J Tyson McDonald Yingli Sun Ewa Micewicz Kelly Pettijohn Robert Damoiseaux Keisuke S Iwamoto James W Sayre Brendan D Price Richard A Gatti William H McBride

PURPOSE Discovery of agents that protect or mitigate normal tissue from radiation injury during radiotherapy, accidents, or terrorist attacks is of importance. Specifically, bone marrow insufficiency, with possible infection due to immunosuppression, can occur after total body irradiation (TBI) or regional irradiation and is a major component of the acute radiation syndrome. The purpose of this...

Journal: :iranian journal of pharmaceutical sciences 0
amir reza jalilian research institute for nuclear medicine, tehran university of medical sciences, tehran, iran aytak novinrooz radiopharmaceutical research and development lab (rrdl), nuclear science and technology research institute (nstri), tehran, iran. sahar sadraee faculty of pharmacy, azad islamic university, tehran, iran. marzieh heydarieh radiopharmaceutical research and development lab (rrdl), nuclear science and technology mehdi akhlaghi radiopharmaceutical research and development lab (rrdl), nuclear science and technology

in the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. among the ligands tested, diacetyl-bis(n4-methylthiosemicarbazones) (atsm) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde bis(n4-methyl)thiosemicarbazone (ptsm) was shown to possess low toxicity (7% let...

Journal: :Public Health Reports (1896-1970) 1961

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