IL: interleukin RAS: recurrent aphthous stomatitis OBSERVATION Recurrent aphthous stomatitis (RAS) is a common cause of recurrent oral ulcers, which often leads to significant impairment of a patient’s quality of life. The underlying pathogenic mechanism remains unclear, and no treatment modality is uniformly effective. In this report, we describe the use of apremilast, an oral phosphodiesteras...

Background: Recurrent aphthous stomatitis (RAS) is the most common inflammatory ulcerative condition of oral cavity. The aim of this study was to compare the levels of the salivary Malondialdehyde (MDA) and total antioxidant capacity (TAC) and blood parameter in RAS versus healthy controls. Methods: This case-control study consisted of 28 patients with RAS and 28 age and sex -matched control...

background: recurrent aphthous stomatitis (ras) is the most common inflammatory ulcerative condition of oral cavity. the aim of this study was to compare the levels of the salivary malondialdehyde (mda) and total antioxidant capacity (tac) and blood parameter in ras versus healthy controls. methods: this case-control study consisted of 28 patients with ras and 28 age and sex -matched control wi...

BACKGROUND AND AIM: Recurrent aphthous stomatitis (RAS) is a lesion of the oral cavity with an unknown etiology. Several studies have been performed on the role of tumor necrosis factor-alpha (TNF-α) in RAS. The main purpose of this paper was to review TNF-α level and its gene polymorphism in patients with RAS, the factors influencing the production of TNF-α, a...

Background and objectives: Recurrent aphthous stomatitis (RAS) is one of the most common painful mucosal diseases seen in the oral cavity of patients. Pathogenesis and etiology of this disorder is still unclear. RAS is categorized into minor, major, and herpetiform ulcers. Ulcers classified as minor, consist more than 85% cases of RAS. The goal of this study was to review the e...

Aims: The study aims to appraise the clinical efficiency of 2% ethanolic thuja orientalis extract in comparison effect kenalog orabase patients with recurrent aphthous stomatitis RAS. Materials and methods: This research included eighty active lesions, twenty were treated extract, orabase, as a control positive, without treatment negative. Results: results showed good effective response topical...

background: anxiety-related traits have been attributed to sequence variability in the genes coding for serotonin transmission in the brain. two alleles, termed long (l) and short (s) differing by 44 base pairs, are found in a polymorphism identified in the promoter region of serotonin transporter gene. the presence of the short allele and ss and ls genotypes is found to be associated with the ...