IL: interleukin RAS: recurrent aphthous stomatitis OBSERVATION Recurrent aphthous stomatitis (RAS) is a common cause of recurrent oral ulcers, which often leads to significant impairment of a patient’s quality of life. The underlying pathogenic mechanism remains unclear, and no treatment modality is uniformly effective. In this report, we describe the use of apremilast, an oral phosphodiesteras...

Abstract Recurrent aphthous ulcers are common painful mucosal conditions affecting the oral cavity. Despite their high prevalence and knowledge of many etiological factors, exact mechanism disease is still not fully understood. There three different clinical forms recurrent stomatitis therapy differs depending on it. The aim this article to provide an overview current about possible causes trea...

Background and Aim. Recurrent aphthous stomatitis (RAS) is a common oral mucosal disorder characterized by recurrent, painful oral aphthae. Despite extensive research, the exact etiology of RAS remains elusive. Recently oxidant-antioxidant imbalance of the body has been implicated in the pathogenesis of recurrent aphthous stomatitis. Thus, the aim of the study was to evaluate the enzymatic anti...

Recurrent aphthous stomatitis consists on recurring oral ulcers of unknown etiology. Oral ulcers may be different in number and size depending on the clinical presentation, which also determines the time needed for healing. Moreover, there are factors associated to outbreaks but not implicated in its etiopathogenesis. When oral aphthosis has a known etiology, it is not considered as recurrent a...

microbial factors may play a role in the pathogenesis of recurrent aphthous stomatitis (ras). because of similarities in the characteristics of peptic ulcers and oral aphthous ulcers, it seems reasonable to hypothesize that helicobacter pylori ( h. pylori ) could play a role in the development of ras. the aim of the present study was to determine the relationship between h. pylori and ras using...

UNLABELLED Recurrent aphthoid stomatitis is characteristically observed in children and adolescents in the form of painful relapsing ulcers in the oral mucosa unaccompanied by evidences of systemic disease. The ulcers appear every one or two weeks for at least one entire year. Some patients suspected for recurrent aphthoid stomatitis develop lesions in atypical sites - mainly in the larynx - co...