objective 1-3% of the population suffer from epilepsy. up to 30% of them develop refractory epilepsy and their seizures occur more than once per month despite receiving at least 2 first line antiepileptic drugs. in  this group, more efficacious antiepileptics are needed. this study was undertaken to evaluate the efficacy and safety of oxcarbazepine as an adjunction therapy in children with refr...

background: the main purpose of the current study was to determine the effect of treating helicobacter pylori (hp) infection on seizure frequency in patients with refractory epilepsy. methods: a small sample of adult patients above 18 years of age with a diagnosis of refractory epilepsy was studied at the outpatient epilepsy clinic at shiraz university of medical sciences, from january 2009 thr...

how to cite this article: aminzadeh v, setila dalili s, ashoorian y, kohmanaee sh, hassanzadeh rad a. anthropometric indices in children with refractory epilepsy. iran j child neurol. winter 2016; 10(1):47-52. abstract objective we aimed to assess the effect of body mass index (bmi) on reducing the risk of refractory seizure due to lipoid tissue factors. materials & methods this matched case-co...

Background: Epilepsy is the second common neurologic disorder. Although many antiepileptic drugs have been formulated to control the seizures, but not all seizures have been controlled by them. Uncontrolled epilepsy can actually reduce the patients’ quality of life. Objectives: Identifying the proportion of adult intractable epilepsy among epileptic patients in an area in the North East o...

dyke-davidoff-masson syndrome (ddms) is a syndrome associated with refractory epilepsy. ddms is a rare syndrome characterized by seizures, facial asymmetry, contralateral hemiplegia and mental retardation. the characteristic radiologic features are cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses. the case was an 18 years old female with seizures, hemiparesis of the ri...

UNLABELLED Obstructive sleep apnea (OSA) commonly coexists with epilepsy, and treatment of OSA may decrease seizure frequency. However, it is unclear whether patients with medically refractory epilepsy have a higher incidence of OSA compared with well-controlled epilepsy patients and whether the two groups carry different risk factors. PURPOSE This study aimed to investigate the presence of O...

Background: Sleep Seizures (SSs) generally occur in refractory focal epilepsy, but their detailed characteristics and circadian patterns are still controversial. The effect of SSs on epilepsy surgery outcome has been addressed in few studies without definitive prognostic value.   Objectives: This study investigated the characteristics of SSs and their prognosis in refractory focal epilepsy. M...

Introduction Biotinidase deficiency is a life threatening inborn error of metabolism specially when delayed in diagnosis. We report a 2-month-old male infant that presented with refractory infantile spasm, alopecia and seborrheic dermatitis. With a high suspicion of the biotinidase deficiency we started biotin 10 mg daily orally before definite diagnosis was made. Rapid treatment was life-savin...