The organization of the actin cytoskeleton plays a key role in regulating cell mechanics. It is fundamentally altered during transformation, affecting how cells interact with their environment. We investigated mechanical properties of cells expressing constitutively active, oncogenic Ras (RasV12) in adherent and suspended states. To do this, we utilized atomic force microscopy and a microfluidi...

The current brief review paper on rock stress measurement methods is very crucial factors in mining, civil infrastructure, geothermal energy, nuclear underground disposal, large oil storage caverns, etc as well geology and geophysical area. Measurement of situ a challenging difficult quantity not possible to measure directly. Measure the deformation or displacements hydraulic by perturbing conv...

one of the most important parameters used for determining the performance of tunnel boring machines (tbms) is their penetration rate. the parameters affecting the penetration rate can be divided in two categories. the first category is the controllable parameters such as the tbm technical characteristics, and type and geometry of the tunnel, and the second one is the uncontrollable parameters s...

Rock abrasivity, as one of the most important parameters affecting the rock drillability, significantly influences the drilling rate in mines. Therefore, rock abrasivity should be carefully evaluated prior to selecting and employing drilling machines. Since the tests for a rock abrasivity assessment require sophisticated laboratory equipment, empirical models can be used to predict rock a...

in this work, the mechanism for fracture of brittle substances such as rocks under a uniform normal tension is considered. the oriented straight micro-cracks are mostly created in all the polycrystalline materials resulting from the stress concentrations. the present work focuses on the interactions of the pre-existing micro-cracks, which can grow and propagate within a rock-like specimen. the ...