Henoch-Schonlein purpura is vasculitis of small blood vessels characterized by deposits of IgA immune complexes and also non-thrombocytopenic purpura, abdominal pain, arthritis and renal involvement. It affects people of all ages, but most cases occur in children between 2 and 11 years old, more frequently in boys. The disease is much less common in adults, who often have a more severe course o...

Bacterial and viral triggers are suspected agents in the initial etiology of autoimmune diseases. There are some studies on the etiology of autoimmune disorders which have focused on streptococcal infection and a possible relation with microbial heat shock proteins (hsp) which show significant homology with human heat shock proteins. In addition, some serotypes of streptococci cross-react ...

Henoch-Schönlein purpura (HSP) is a systemic vasculitis characterized classically by purpura, arthritis and abdominal pain. Epididymitis/orchitis is rarely seen as a complication of HSP. Testicular or scrotal involvement has been reported in children with Henoch-Schonlein purpura and must be distinguished from testicular torsion. We report a case of a 5 year old boy diagnosed with Henoch-Schönl...

We present a child with Henoch-Schonlein purpura and Mycoplasma pneumoniae infection, an association that was rarely described in the literature. The infection was confirmed serologically and by using PCR.

1 of 1 DESCRIPTION A 63-year-old man with a history of intermittent vasculitic rash presented with an acute abdomen. Findings at laparotomy were consistent with patchy serosal small vessel vasculitis. The patient was well and walking around the ward 24 h later after intravenous methylprednisolone. In this case no biopsy was taken. The diagnosis was made clinically given the history of intermitt...

Henoch Schonlein purpura is a systemic vasculitis that commonly affects children and teenagers but also affects adults of all ages. In most instances it has a benign course. Organ involvement, particularly in adults, and notably the kidneys and gastrointestinal tract may require therapeutic intervention and may have a less favorable outcome. We report a case of a 58-year-old man who presented w...

A 63-year-old woman with abdominal pain and melena developed a palpable, purpuric rash and acute kidney injury. Skin and kidney biopsy confirmed Henoch-Schönlein purpura. Upper endoscopy revealed diffuse, circumferential, black-appearing mucosa of the esophagus consistent with acute esophageal necrosis (AEN), also known as black esophagus. AEN is a very rare cause of gastrointestinal hemorrhage...

Henoch-Schönlein purpura (HSP) is a small vessel vasculitis that annually affects 10 to 20 children per 100,000 population. It is the most common vasculitis of childhood. Although HSP is seen in infancy through adulthood, most documented cases affect children; more than 75% of those diagnosed as having HSP are younger than 10 years, with a peak incidence at 4 to 6 years. White and Asian childre...

during a 6 year period from september 1992 to september 1998, 165 children with a final diagnosis of henoch-schonlein purpura (hsp) were managed and followed in our center. there were 87 (52%) boys and 78 (48%) girls, with age ranges of 1-16 years and mean age of 7.8 years. forty-one percent of the patients had evidence of preceding upper respiratory tract infection (uri). the main clinical fea...