Scorpion venom contains a variety of biologically active peptides. Among them, neurotoxins are major components in the venom, but it also peptides that show antimicrobial activity. Previously, we identified three insecticidal from Liocheles australasiae scorpion, activities and structures other remained unknown. In this study, performed transcriptome analysis gland scorpion L. to gain comprehen...

Scorpion venom is a rich source of biomolecules, which can perturb physiological activity of the host on envenomation and may also have a therapeutic potential. Scorpion venoms produced by the columnar cells of venom gland are complex mixture of mucopolysaccharides, neurotoxic peptides and other components. This study was aimed at cataloguing the elemental composition of venoms obtained from me...

Introduction Accidental scorpion sting is a serious health issue of poor communities in tropical and subtropical areas throughout the world. Out of 1500 scorpion species distributed throughout the world, only 50 scorpion species have been proved lethal to human [1]. The symptoms of scorpion envenomation depend on species, age, venom composition and the victim’s physiological response. Scorpion ...

The yellow Iranian scorpion Odontobuthus doriae can cause fatal envenoming, but its mechanism of action is unclear. One of the reported manifestations of envenoming is moderate to severe involuntary tremor of skeletal muscle. In order to understand better the mechanism of action of this venom on skeletal muscle function, we examined the effects of the venom in vitro on chick biventer cervicis (...

Scorpions are one of the most ancient groups of terrestrial animals. They have maintained a steady morphology over more than 400 million years of evolution. Their venom arsenals for capturing prey and defending against predators may play a critical role in their ancient and conservative appearance. In the current review, we present the scorpion fauna of China: 53 species covering five families ...

Scorpions belong to class arachnide and are quite commonly encountered in India. The scorpions venom containing short neurotoxin polypeptides consists of low molecular weight proteins, Which have mechanisms of lethal and paralytic effect. In many tropical and subtropical countries, venoms from medically important scorpion species are still used in the production of anti-venoms to the treatment ...

background : antivenom is still widely used in the treatment of envenomation as there are no vaccines or other effective agents available against animal venoms. recently, neurotoxins named birtoxin family have been described from parabuthus transvaalicus and androctonus crassicauda. the aim of the present study was to test the antibirtoxin antibodies for their ability to neutralize the lethal e...

BACKGROUND Antivenom is still widely used in the treatment of envenomation as there are no vaccines or other effective agents available against animal venoms. Recently, neurotoxins named birtoxin family have been described from Parabuthus transvaalicus and Androctonus crassicauda. The aim of the present study was to test the anti-birtoxin antibodies for their ability to neutralize the lethal ef...

Buthotus schach is one of the dangers scorpion in Iran that belong to the Buthidae family. Toxins are existing in venom scorpion, modulate the ion channels by blocking or opening the pore of the channel or by altering the voltage gating and useful as pharmacological tools. In the present study, we investigated the effect of venom and its obtained fractions by gel filtrations on electrophysiolog...

introduction: scorpion venoms contain a variety of peptides, toxic to mammals، insects and crustaceans and are the main factors in scorpion venom toxicity (their amount being 1-3% of total venom). most of the scorpion toxins have been isolated from the venoms of scorpions in the buthidae family. the scorpion buthotus schach of this family is widely found in the western regions of iran, but no p...