CDK1 (cyclin dependent kinase 1) is a key regulator of the cell cycle and frequently dysregulated in cancer, making it promising target for anticancer therapy. Securigera securidaca L. (S. securidaca) seeds, traditionally used folk medicine various ailments including were examined their potential as CDK1/Cks2 inhibitors using silico approaches. A total 14 phytocompounds was identified GC/MS chr...

Although Securigera securidaca (Ss) has long been known for its hypoglycemic effect, the precise nature of its effective component(s) and the involved mechanisms have not been investigated yet. This study investigated the effect of chloroformic extract of securigera securidaea seed on fasting serum glucose and glucose tolerance test, body weight, food consumption and liver glycogen content. Chl...

Abstract A field experiment was carried out in Diyala Governorate during the winter season 2020-2021 to evaluate effect of spraying three concentrations Brassinolide hormone (1, 2 and 3 ppm) addition control treatment (0 dates (after 20,40 60 days germination) production oil total glycosides Securigera securidaca seeds, by using a factorial according randomized complete block design. The result...

Essential oils of eight plants, selected after an ethnobotanical survey conducted in Bukusu community in Bungoma County, western Kenya (Tagetes minuta, Tithonia diversifolia, Juniperus procera, Solanecio mannii, Senna didymobotrya, Lantana camara, Securidaca longepedunculata, and Hoslundia opposita), were initially screened (at two doses) for their repellence against brown ear tick, Rhipicephal...

securigera securidaca (l.) degen & dorfl grows in different parts of iran. the seeds of the species are used in iranian folk medicine as an anti-diabetic agent. many studies have established hypoglycemic effects of amino acids and in the present investigation, amino acids of securigera securidaca seeds have been evaluated. the ground seeds were extracted using petroleum ether, hot ethanol a...