Background and objectives: The seeds of Securigera securidaca (L.) Deg. & Dorf. (Fabaceae) are used as anti-diabetic remedy in Iranian folk medicine. The aim of the present study was to establish the callus and suspension culture of S. securidaca seeds for the first time and to determine the major secondary metabolites including cardiac glycosides and total phenols. Methods: The culture of S. s...

S. securidaca seeds are reported to treat a variety of diseases; they contain multiple antidiabetic constituents and widely used as anti-hyperglycemic, antibacterial, well anti-hyperlipidemic agents. The present work aimed propose tablet formulations containing extracts in an attempt obtain antibacterial anti-hyperglycemic with more efficient oral hypoglycemic impact, limited side effects, high...

Diabetes mellitus is associated with dysregulation of adipose tissue metabolism and increased level of serum lipids. In our previous work we found that Securigera securidaca decreases cholesterol level in blood of diabetic rats. The present study was carried out to further investigate the effects of this plant on lipid metabolism, lipolysis, and adipogenesis, in diabetic rats. Female Wistar rat...

Rosa damascena, Tripleurospermum disciforme and Securigera securidaca were used as disinfectant agents and for treatment of some disease in folk medicine of Iran. The antimicrobial effects of different fractions of seeds extract of S. securidaca, petals extract of R. damascena and aerial parts extract of T. disciforme were examined against some gram positive, gram negative and fungi by cup plat...

Securigera securidaca (Fabaceae) or goat pea is growing wild in West Asia, Europe and Africa as an annual herb. In Persian, it is called “Gandeh Talkheh”. The seeds of goat pea are applied in the traditional medicine to treat different dysfunctions e.g., hyperlipidemia and hypertension. This study was done at altitude of 2100 m above sea level. The effects of dietary Securigera securidaca seed ...

rosa damascena, tripleurospermum disciforme and securigera securidaca were used as disinfectant agents and for treatment of some disease in folk medicine of iran. the antimicrobial effects of different fractions of seeds extract of s. securidaca, petals extract of r. damascena and aerial parts extract of t. disciforme were examined against some gram positive, gram negative and fungi by cup plat...

Securigera securidaca (L.) Degen & Dorfl grows in different parts of Iran. The seeds of the species are used in Iranian folk medicine as an anti-diabetic agent. Many studies have established hypoglycemic effects of amino acids and in the present investigation, amino acids of Securigera securidaca seeds have been evaluated. The ground seeds were extracted using petroleum ether,...

background and objectives: the seeds of securigera securidaca (l.) deg. & dorf. (fabaceae) are used as anti-diabetic remedy in iranian folk medicine. the aim of the present study was to establish the callus and suspension culture of s. securidaca seeds for the first time and to determine the major secondary metabolites including cardiac glycosides and total phenols. methods: the culture of s. s...

the search for indigenous natural antidiabetic agents is still ongoing. securigera securidaca seeds are reputed in folk medicine for their value as an antidiabetic remedy, so the present study was carried out to investigate the hypoglycemic efficacy in both normal and streptozotocine (stz)-induced diabetic rats. hydroalcoholic extract of the seeds were administered orally with doses of 200, 400...