introduction: barrel cortex of rats is a part of somatosensory cortex, which receives information from facial whiskers. vibrisectomy by sensory deprivation leads to some changes in the barrel cortex, which have been known as experience dependent plasticity. on the other hand, norepinephrine (ne) and locus coeruleus, which is the main source of ne, influenced response properties of cortical barr...

Introduction: Barrel cortex of rodents is responsible for sensory information processing from muzzle whiskers. Locus coeruleus (LC) as the main source of norepinephrine (NE) in the cortex, is effective on the sensory information processing. Methods: Rats were divided to 2 groups. One group underwent sensory deprivation (P4) and the other group served as control and did not undergo sensory d...

introduction: it is believed that locus coeruleus (lc) influences the sensory information processing. however, its role in cortical surround inhibitory mechanism is not understood. in this experiment, using controlled mechanical displacement of whiskers we investigated the effect of phasic electrical stimulation of lc on response of layer v barrel cortical neurons in anesthetized rat. methods: ...

Introduction: It is believed that Locus Coeruleus (LC) influences the sensory information processing. However, its role in cortical surround inhibitory mechanism is not understood. In this experiment, using controlled mechanical displacement of whiskers we investigated the effect of phasic electrical stimulation of LC on response of layer V barrel cortical neurons in anesthetized rat. Methods: ...

The factors controlling the specification and subsequent differentiation of sensory neurons are poorly understood. Data from embryological manipulations suggest that either sensory neuron fates are specified by the targets they encounter or sensory neurons are considerably more "plastic" with respect to specification than are neurons of the CNS. The prevailing view that sensory neurons are spec...