Vahid Sheibani

[ 1 ] - Maternal feeding with walnuts (Juglans regia) improves learning and memory in their adult pups

Objective: Walnut (Juglans Regia) is a domestic fruit of Iran. Walnut kernel (WK) has many beneficial constituents such as unsaturated fatty acids, antioxidants, and vitamin E. Scientific studies have shown that fatty acids and vitamin E can modulate learning and memory processes. The aim of the present work was to study effects of walnut consumption by mothers during pregnancy and lactation on...

[ 2 ] - The effects of co-administration of opium and morphine with nicotine during pregnancy on spatial learning and memory of adult male offspring rats

Objective(s): Smoking opium/cigarette is a global health concern. The aim of this study was to examine learning and memory of rat male offsprings whose mothers had been exposed to either opium or morphine with nicotine during pregnancy. Materials and Methods: Wistar rats were used for the experiments. In the female rats, opium, morphine and nicotine dependencies were induced by daily injection...

[ 3 ] - Study the Antinociceptive Effect of Intracerebroventricular Injection of Aqueous Extract of Origanum Vulgare Leaves in Rat: Possible Involvement of Opioid System

  Objective(s): The aim of study was to investigate the antinociceptive effect of intracerebroventricular (ICV) microinjection of Origanum vulgare (ORG) extract and possible involvement of opioid receptors.   Materials and Methods: Cannula was inserted into left ventricle of male rats. Five days after surgery Tail Flick Latency (TFL) was measured after ICV microinjection of, ORG (1, 3 and 6 μg ...

[ 4 ] - The Effect of Opium Dependency of Parent (s) on Offspring’s Spatial Learning & Memory in Adult Male Rats

Objective(s):As far as we know,there has been no report regarding the effects of opium addiction or dependency of both parents on the learning and memory process in offspring. The aim of this study was to examine the learning and memory changes of adult male offspring whose mothers, fathers and/or both parents had dependency to opium before and during pregnancy. Materials and Methods: All exper...

[ 5 ] - The Role of Capsaicin-induced Acute Inactivation of C-fibers on Tactile Learning in Rat

[ 6 ] - Evaluation of Origanum Vulgare L. ssp. Viridis Leaves Extract Effect on Discrimination Learning and LTP Induction in the CA1 Region of the Rat Hippocampus

Objective(s) The objective of this study was to determine the effect of aqueous extract of Origanum vulgare L. ssp. Viridis (ORG) on discrimination learning and long term potentiation (LTP) in CA1 region of the rat hippocampus. Materials and Methods A group of adult male Wistar rats weighing 275±25 g received aqueous extract of ORG (150, 300, 450 mg/kg/day) by intraperitoneal injection for one ...

[ 7 ] - Pre-treatment with erythropoietin attenuates bilateral renal ischemia-induced cognitive impairments

One of the most common causes of mortality in acute kidney injury is brain dysfunction. Here we investigated the possible protective effect of erythropoietin (EPO) on cognitive impairments induced by bilateral renal ischemia (BRI). Eighty male Wistar rats were allocated into 8 groups: 1, 2) Sham+V (Vehicle), 3, 4) Sham+EPO, 5, 6) BRI+V, 7, 8) BRI+EPO. The groups followed by the reperfusion per...

[ 8 ] - Pre-treatment with erythropoietin attenuates bilateral renal ischemia-induced cognitive impairments

One of the most common causes of mortality in acute kidney injury is brain dysfunction. Here we investigated the possible protective effect of erythropoietin (EPO) on cognitive impairments induced by bilateral renal ischemia (BRI). Eighty male Wistar rats were allocated into 8 groups: 1, 2) Sham+V (Vehicle), 3, 4) Sham+EPO, 5, 6) BRI+V, 7, 8) BRI+EPO. The groups followed by the reperfusion per...

[ 9 ] - اثر محرومیت حسی و تحریک الکتریکی فازیک هسته لوکوس سرولئوس به دنبال جا به جایی ویسکر کناری بر ویژگی های پاسخ نورون های لایه IV قشر بشکه ای در موش صحرایی نر

مقدمه: قشر بشکه ای در جوندگان مسول دریافت و پردازش اطلاعات حسی از ویسکرهای صورت حیوان می باشد. هسته لوکوس سرولئوس (LC) منبع اصلی نوراپی نفرین قشر مغز بوده و در پردازش اطلاعات حس تماس موثر است. در این مطالعه اثر تحریک الکتریکی فازیک LC و محرومیت حسی به دنبال جا به جایی ویسکر کناری بر خصوصیات پاسخی نورون های لایه چهار قشر بشکه ای در موش صحرایی نر بررسی شد.مواد و روش ها: خصوصیات پاسخ دهی 18 نورون ...

[ 10 ] - بررسی مروری اثرات محرومیت از خواب بر یادگیری و حافظه: نقش هورمونهای جنسی

  Background and Objectives: Studies have indicated that sleep is essential for the development and survival of the brain and increases the brain's capacity for cognitive functions, and sleep loss disrupts cognitive performance. The present review study aimed to investigate the effects of sleep deprivation on learning and memory with an emphasis on the role of sex hormones. Materials and...

[ 11 ] - اثر تحریک الکتریکی هسته رافه خلفی بر پاسخ برانگیخته نورون‌های لایه IV و V‌‌‌ قشر بارل (بشکه‌ای) در موش صحرایی

Effect of the Dorsal Raphe Nucleus Electrical Stimulation on Evoked Response of the IV Layers and V Barrel Cortical Neurons in Rat M.R Afarinesh MSc , V. Sheibani PhD , R. Farazifard MSc 1, M. Abasnegad PhD , A. Shamsi zadeh MSc Received: 17/09/06 Sent for Revision: 13/03/07 Received Revised Manuscript: 13/06/07 Accepted: 27/06/07 Background and Objective: Seretonergic pathway is one of the neu...

[ 12 ] - P 6: Effect of Voluntary Exercise on Learning and Memory Impairments in Sleep Deprived Female Rats

Introduction: Sleep disorders are common problems in modern societies affecting different aspects of individuals' lives. Many studies have reported that sleep deprivation (SD) leads to impairments in hippocampus-dependent learning and memory formations. Physical exercise has been shown to improve learning and memory. The objective of the current study was to investigate the effects of Voluntary...

[ 13 ] - Low Frequency Stimulation Reverses the Kindling-Induced Impairment of Learning and Memory in the Rat Passive-avoidance Test

Introduction: The life quality of patients with epileptic seizures is highly affected by cognitive deficits. Low Frequency Stimulation (LFS) is a novel approach for the treatment of pharmacoresistant epilepsy. The main goal of this research is investigating the possible effect of LFS on seizure-induced cognitive dysfunction.  Methods: To this end, the kindled animal were prepared via CA1 ...

[ 14 ] - Antiamnesic Effects of Walnuts Consumption on Scopolamine- Induced Memory Impairments in Rats

Introduction: Alzheimer’s disease (AD) is an age-related neurodegenerative disease, which impairs memory and cognitive function. Walnuts are a dietary source of polyphenols, antioxidants and other compounds with health beneficial effects. These characteristic of walnuts make them perfect candidates for evaluation of their possible effects on neurodegenerative diseases. Therefore the prese...

[ 15 ] - Caffeine improved spatial learning and memory deficit in sleep deprived female rat

Previous studies have shown that caffeine has beneficial effects on cognitive impairment in sleep deprived male rats. Therefore in the present study, we examined the effects of chronic caffeine administration on learning and memory impairments induced by sleep deprivation (SD) in the intact and ovarectomized (OVX) female rats. Two sets of animals including intact and OVX were randomly recruited...

[ 16 ] - Effect of sensory deprivation and Locus Coeruleus (LC) electrical stimulation on the response properties of layer IV barrel cortex neurons in male rats

Introduction: Barrel cortex of rodents is responsible for sensory information processing from muzzle whiskers. Locus coeruleus (LC) as the main source of norepinephrine (NE) in the cortex, is effective on the sensory information processing. Methods: Rats were divided to 2 groups. One group underwent sensory deprivation (P4) and the other group served as control and did not undergo sensory d...

[ 17 ] - Effect of Norepinephrine depletion on induction of experience dependent plasticity in male rat barrel cortex

Introduction: Barrel cortex of rats is a part of somatosensory cortex, which receives information from facial whiskers. Vibrisectomy by sensory deprivation leads to some changes in the barrel cortex, which have been known as experience dependent plasticity. On the other hand, Norepinephrine (NE) and locus coeruleus, which is the main source of NE, influenced response properties of cortical bar...

[ 18 ] - Neuronal response properties of somatosensory cortex (layer IV) are modulated following experience dependent plasticity in c-fiber depleted rats

Previous studies have shown that the receptive field properties, spontaneous activity and spatio-temporal interactions of low-threshold mechanical somatosensory cells in the barrel cortex are influenced by C-fibers. In this study, we examined the effect of C-fiber depletion on response properties of barrel cortex neurons following experience dependent plasticity. Methods: In this study, exte...

[ 19 ] - Effects of REM sleep deprivation during pregnancy on spatial learning of adult male offspring of rats

Introduction: There are several evidences that show various environmental stresses during pregnancy, affect physiological behavior of the offspring. In this study the effects of REM (Rapid Eye Movement) sleep deprivation of pregnant rats on spatial learning of adult male offspring by Morris water maze were investigated. Methods: Water tank technique was used for inducing REM sleep deprivatio...

[ 20 ] - Effect of phasic electrical locus coeruleus stimulation on inhibitory and excitatory receptive fields of layer V barrel cortex neurons in male rat

Introduction: It is believed that Locus Coeruleus (LC) influences the sensory information processing. However, its role in cortical surround inhibitory mechanism is not understood. In this experiment, using controlled mechanical displacement of whiskers we investigated the effect of phasic electrical stimulation of LC on response of layer V barrel cortical neurons in anesthetized rat. Methods: ...

[ 21 ] - Knowledge of Dentistry, Medicine, and Pharmacy Students about Psychedelic Drugs in Kerman University of Medical Sciences

Abstract Background: Psychedelic drugs can cause one to get out of normal status and permanent cerebral defects, via affecting central nervous system. Consumption of theses drugs seems to be increasing nowadays especially among the youth and university educated population. We conducted a study to evaluate the awareness of medical science students of Kerman University of medical scie...

[ 22 ] - Zataria multiflora Boiss. extract improves spatial memory and learning capacity in scopolamine-induced amnesic rats

Objective: Zataria multiflora (Zm) has been proposed for memory enhancing in Persian traditional medicine; but to now, no study has been carried out in this field yet. The aim of this research was to study the plant effect on spatial memory in scopo...

[ 23 ] - An Standardized Extract From Textured Soy Protein (Glycine Max L.) Has Ameliorating Effect on Memory Deficit and Learning Insufficiency in Scopolamine-Induced Amnesia

Purpose of the Study: Textured soy protein (TSP) and Ajil are two processed forms of soybean (Glycine max L.) which are widely consumed by Iranian for nutritional purpose. Recently, we have reported antioxidant and anticholinesterse effect of raw soybean (RS) which has been attributed to isoflavones such as genistein. In this work, we aimed to compare in vitro antioxidant and antichoinesterase ...