Mohammad Shabani
Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, I. R. Iran
[ 1 ] - Maternal feeding with walnuts (Juglans regia) improves learning and memory in their adult pups
Objective: Walnut (Juglans Regia) is a domestic fruit of Iran. Walnut kernel (WK) has many beneficial constituents such as unsaturated fatty acids, antioxidants, and vitamin E. Scientific studies have shown that fatty acids and vitamin E can modulate learning and memory processes. The aim of the present work was to study effects of walnut consumption by mothers during pregnancy and lactation on...
[ 2 ] - Angiotensin II type 1 receptor blocker losartan attenuates locomotor, anxiety-like behavior and passive avoidance learning deficits in a sub-chronic stress model
Objective(s): Stress alters sensory and cognitive function in humans and animals. Angiotensin (AT) receptors have demonstrated well-established interactions in sets of physiological phenomena. AT1 receptors can play a part in stress-induced activation of hypothalamic-pituitary-adrenal (HPA) axis; besides angiotensinergic neurotransmission plays a pivotal role in stress-evoked physiological resp...
[ 3 ] - Pre-treatment with erythropoietin attenuates bilateral renal ischemia-induced cognitive impairments
One of the most common causes of mortality in acute kidney injury is brain dysfunction. Here we investigated the possible protective effect of erythropoietin (EPO) on cognitive impairments induced by bilateral renal ischemia (BRI). Eighty male Wistar rats were allocated into 8 groups: 1, 2) Sham+V (Vehicle), 3, 4) Sham+EPO, 5, 6) BRI+V, 7, 8) BRI+EPO. The groups followed by the reperfusion per...
[ 4 ] - Pre-treatment with erythropoietin attenuates bilateral renal ischemia-induced cognitive impairments
One of the most common causes of mortality in acute kidney injury is brain dysfunction. Here we investigated the possible protective effect of erythropoietin (EPO) on cognitive impairments induced by bilateral renal ischemia (BRI). Eighty male Wistar rats were allocated into 8 groups: 1, 2) Sham+V (Vehicle), 3, 4) Sham+EPO, 5, 6) BRI+V, 7, 8) BRI+EPO. The groups followed by the reperfusion per...
[ 5 ] - مقایسه تاثیر ایزوفلوران و پروپوفول بر عمق بیهوشی و حجم خونریزی در جراحی آندوسکوپیک سینوس
سابقه و هدف: جراحی آندوسکوپیک سینوس یکی از جراحیهایی است که نیاز به محل تمیز جراحی دارد. هدف از این مطالعه بررسی اثر پروپوفول در مقایسه با ایزوفلوران روی عمق بیهوشی و نیز رابطه احتمالی آن با میزان خونریزی حین آندوسکوپی سینوس است. مواد و روشها: تعداد 52 بیمار مراجعه کننده به بیمارستان شفا کرمان شامل 16 زن و 36 مرد تحت عمل آندوسکوپی سینوس جهت این کارآزمایی بالینی انتخاب شدند. در گروه اول پروپو...
[ 6 ] - مقایسه اثر فنتانیل، سوفنتانیل و آلفنتانیل به عنوان پره مدیکاسیون بر بروز تهوع و استفراغ بعد از عمل جراحی لاپاروسکوپی تشخیصی ژنیکولوژیک
سابقه و هدف: کاهش بروز تهوع و استفراغ پس از عمل (Postoperative nausea and vomiting, PONV) سبب تسریع ترخیص بیماران شده و هزینه‌های مربوط به داروهای ضدتهوع و استفراغ و مدت زمان توقف بیمار و یا بستری مجدد را کاهش می‌دهد و زمینه رضایت‌مندی بیش‌تر بیماران را فراهم می‌کند. در این مطالعه اثر سه داروی مخدری که به طور رایج در بیهوشی عمومی مورد استفاده قرار می‌گیرد (آلفنتانیل، فنتانیل و سوفنتانیل...
[ 7 ] - Low Frequency Stimulation Reverses the Kindling-Induced Impairment of Learning and Memory in the Rat Passive-avoidance Test
Introduction: The life quality of patients with epileptic seizures is highly affected by cognitive deficits. Low Frequency Stimulation (LFS) is a novel approach for the treatment of pharmacoresistant epilepsy. The main goal of this research is investigating the possible effect of LFS on seizure-induced cognitive dysfunction. Methods: To this end, the kindled animal were prepared via CA1 ...
[ 8 ] - Evaluation of wound healing and post-operative intra-abdominal adhesions in opium addicted rats
Introduction: Opium addiction can change immune response to Types of stress such as injury or trauma due to alterations in the in secretion status of cytokines in the body. In this study, effects of opium addiction on wound healing and post-operative adhesion bands were assessed after laparotomy. Materials and Methods: Male rats (n=20) were randomly divided into opium addicted (documented with ...
[ 9 ] - Nitric oxide system modulates hyperalgesia and memory impairments following psycophysical stress
Introduction: Sub-chronic swim stress is known to induce a prolonged hyperalgesia, which is mediated through NMDA and opioid systems. Nitric oxide is a soluble gas, which acts as a retrograde messenger that modulates the release of mentioned neurotransmitters. It is also involved in nociception and memory. The aim of this study was to evaluate the role of NO pathway in nociception and memory...
[ 10 ] - Mobile phone exposure during pregnancy disrupts learning and memory in rat offsprings
Abstract Introduction: Mobile phones create high-frequency electromagnetic fields around them when in use. The close proximity of mobile phones to the user’s head leads to the absorption of part of the electromagnetic waves into the head and the brain. Methods: We have elucidated the alteration in cognitive function of the male and female offspring rats, which were exposed to chronic mobi...
[ 11 ] - Effect of Acute administration of Cisplatin on memory, motor learning, balance and explorative behaviours in Rats
Introduction: For some cancer survivors chemotherapy treatment is associated with lasting motor and cognitive impairments, long after treatment cessation. Cisplatin as an anti-neoplastic agent is extremely toxic and can cause severe tissue damage. In the present study, we elucidated alteration in performance of hippocampus- and cerebellum-related behaviors following acute cisplatin treatmen...
[ 12 ] - بررسی اثرات مخرب مصرف WIN 55212-2، آگونیست گیرنده کانابینویید، در دوران حاملگی بر عملکرد سیستم اعصاب مرکزی نوزادان موش‌های صحرایی
Introduction: Cannabinoid consumption including hashish and WIN55212-2 during pregnancy has destructive affect on the development of fetus and the performance of CNS. Method: WIN treated group received daily 0.5 or 1mg/kg WIN suspended in 1% tween 80 saline (s.c.) at a volume of 1 ml/kg from days 5 to 20 of pregnancy. Third, fifth and seventh weeks after birth, the effects of maternal WIN ...
[ 13 ] - Morphine in Plasma and Cerebrospinal Fluid of Patients Addicted to Opiates Undergoing Surgery: High-performance Liquid Chromatography Method
Background: The prevalence of opium addiction among Iranians is considerable. Since endogenous opioid systems may be altered as a consequence of addiction, it is very important to determine the plasma and cerebrospinal fluid (CSF) levels of morphine in Iranian patients addicted to opiates who will undergo surgery.Methods: We obtained CSF and plasma samples from 50 volunteers with an established...
[ 14 ] - Attenuation Effect of Cannabinoid Type 1 Receptor Activation on Methamphetamine-Induced Neurodegeneration and Locomotion Impairments among Male Rats
Background: A number of neuroimaging studies on human addicts have revealed that abuse of Methamphetamine (METH) can induce neurodegenerative changes in various brain regions like the cerebral cortex and cerebellum. Although the underlying mechanisms of METH-induced neurotoxicity have been studied, the cellular and molecular mechanisms of METH-induced neurotoxicity remain to be clarified. Previ...
[ 15 ] - Estrogen and Progesterone Replacement Therapy Prevent Methamphetamine-Induced Synaptic Plasticity Impairment in Ovariectomized Rats
Background: Methamphetamine (METH) is one of the most popular psychostimulants which produce long lasting learning and memory impairment. Previous studies have indicated that estrogen and progesterone replacement therapy attenuate cognitive impairment against a wide array of neurodegenerative diseases. Present study was designed to figure out the effects of estrogen, progesterone alone or in co...
[ 16 ] - Destructive Effects of Prenatal WIN 55212-2 Exposure on Central Nervous System of Neonatal Rats
Background: Cannabinoid, particularly hashish and WIN 55212-2 (WIN), consumption during embryonic period may affect fetal growth, and the development of motor functioning, memory and cognitive functions. Therefore, the present study aimed to evaluate the effects of WIN 55212-2 during embryonic period on behavioral responses, as well as tissue and memory changes among neonatal rats. Methods: WIN...
[ 17 ] - Evaluation of Mexiletine Effect on Bispectral Index Changes and Hemodynamic Responses to Endotracheal Intubation and During General Anesthesia
Background &Objective: Plaryngoscopy and tracheal intubation increase not only blood pressure and heart rate but also Bispectral Index (BIS) of the patients. In this study, hemodynamic and BIS changes were surveyed after tracheal intubation and during general anesthesia followed by mexiletine prescription . Materials & Methods: In this study, 50 patients aged between 20 and 60 who were ca...
[ 18 ] - Evaluation of intra ocular pressure and hemodynamic change following intubation with Maccoy, Macintosh and Video laryngoscope
Background & Objective: The induction of anesthesia, laryngoscopy and endotracheal intubation can be associated with adverse hemodynamic response and increased intraocular pressure. The aim of this study was to evaluate intraocular pressure and hemodynamic changes after laryngoscopy and endotracheal intubation with three methods of laryngoscopy (Macintosh, Maccoy and Video laryngoscope).Materia...
[ 19 ] - A Feasibility Study of IMRT of Lung Cancer Using Gafchromic EBT3 Film
Background: Intensity modulated radiation therapy (IMRT) is an advanced method for delivery of three dimensional therapies, which provides optimal dose distribution with giving multiple nonuniform fluency to the patient. The complex dose distribution of IMRT should be checked to ensure that the accurate dose is delivered. Today, film dosimetry is a powerful tool for radiotherapy treatment Quali...
[ 20 ] - Ischemic Postconditioning Attenuates Bilateral Renal Ischemia-Induced Cognitive Impairments
Background and aim: Acute kidney injury (AKI) is a frequent complication of kidney failure with high mortality which leads to brain dysfunction. The aim of this study was to investigate the possible protective effect of ischemic postconditioning (IPo) against brain dysfunction induced by bilateral renal ischemia (BRI). Materials and methods: Male Wistar rats underwent BRI, sham or IPo surgery ...
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