BACKGROUND In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocytopenia, in particular, immune-mediated thrombocytopenia (immune thrombocytopenia) that usually manifests with severe thrombocytopenia. RESULTS Sera were collected from 64 out...

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Background: Determining the prevalence and risk factors of thrombocytopenia among neonates enables us to prevent the inevitable and sometimes irreversible complications. In this study we aimed to survey the frequency of thrombocytopenia and its demographic features and risk factors. Materials and methods: In this cross sectional study the platelet counts of 364 neonates admitted to neonatal ...

BACKGROUND Thrombocytopenia is one of the most common laboratory abnormalities encountered in patients with severe sepsis. It has been reported that thrombocytopenia is linked to mortality in patients with severe sepsis. However, the mechanism of thrombocytopenia in sepsis is unknown. We hypothesized that inflammatory cytokines and microRNAs (miRNAs) are not only involved in the pathogenesis of...

background: determining the prevalence and risk factors of thrombocytopenia among neonates enables us to prevent the inevitable and sometimes irreversible complications. in this study we aimed to survey the frequency of thrombocytopenia and its demographic features and risk factors. materials and methods: in this cross sectional study the platelet counts of 364 neonates admitted to neonatal int...

amegakaryocytic thrombocytopenia (amt) is a rare cause of acquired thrombocytopenia. the pathogenesis and treatment of amt is not clearly known. here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. the patient did not respond to intravenous immunoglob...

Idiopathic thrombocytopenia purpura (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia and mucocutaneous bleeding. The former has a primary role in the diagnosis and treatment of ITP. One of the leading causes of miscounted platelets in patients who suffer from ITP is giant platelets which may indicate factitiously a severe false thrombocytopenia. Here, a case of macroth...

OBJECTIVES Thrombocytopenia is defined as a platelet count of < 150 × 10⁹/L. It is a common hematologic abnormality during pregnancy. Evaluation and treatment of gestational thrombocytopenia can be both, expensive and invasive, and may result in an adverse outcome. The aim of our study was to investigate the incidence of perinatal complications in pregnancies complicated with gestational thromb...