severe thrombocytopenia with bleeding is rarely reported in children with brucellosis, and recurrent epistaxis is extremely rare. brucellosis with hemorrhage should be differentiated from viral hemorrhagic fever, malignancy, and other blood disorders. bone marrow aspiration (bma) is mandatory to differentiate from other blood diseases. an 8-year-old boy was admitted with recurrent epistaxis, pe...

Abstract Background Thrombocytopenia is the most common hematological abnormality which is encountered in the neonatal intensive care unit (NICU). The incidence in neonates varies greatly, depending upon the population studies. According to the frequency of thrombocytopenia and its complications and because of lack of such research in Iran, this study was performed on neonates admitted to Sha...

Treatment of severe Immune Thrombocytopenic purpura (ITP) accompanied by life-threatening bleeding events is challenging and a combination of treatment measures should be undertaken to rapidly increase the platelet count. Herein, we report a case of severe ITP in a seven-year-old boy who suffered from massive bleeding which was totally unresponsive to conventional therapeutic interventions. Sin...

in systemic lupus erythematosus- (sle) various antibodies are produced against cells including platelets and result in thrombocytopenia. in the literature, the incidence of thrombocytopenia varied from 7% to 52%, in seven series of sle patients with a mean cumulative percentage of 14.5% (1-5). sle patients referred to the lupus unit of the rheumatology research center, tehran university for med...

conclusions the authors describe the second reported case of eptifibatide-induced severe thrombocytopenia associated with cardiac surgery. in this case, discontinuation of eptifibatide and transfusion of apheresis platelets increased the platelet count (137 k/ul) the following day, and the patient subsequently underwent successful coronary artery surgery using cardiopulmonary bypass. introducti...

conclusions in critically ill patients, the symptoms of hypophosphatemia may not be apparent, but clinicians should be vigilant about this complication during therapy. in cases of severe symptoms (e.g., cardiopulmonary distress, anemia and thrombocytopenia, or rhabdomyolysis), phosphate therapy under close surveillance is warranted. introduction although asymptomatic hypophosphatemia is a commo...

splenomegaly-induced thrombocytopenia is fully described in hematological and surgical literature, but its association with severe aortic stenosis is rare. we present a case of severe aortic valve stenosis with severe splenomegaly-induced thrombocytopenia in which aortic valve replacement was done with a number 23 homograft and splenectomy was performed after the end of cardiopulmonary bypass. ...

treatment of severe immune thrombocytopenic purpura (itp) accompanied by life-threatening bleeding events is challenging and a combination of treatment measures should be undertaken to rapidly increase the platelet count. herein, we report a case of severe itp in a seven-year-old boy who suffered from massive bleeding which was totally unresponsive to conventional therapeutic interventions. sin...