Turbidity currents in the ocean and lakes are driven by suspended sediment. The vertical profiles of velocity and excess density are shaped by interaction between the current and bed as well as between the current and the ambient water. This paper presents 48 series of experiments in which saline gravity currents flow through a laboratory sinuous flume. flume contains three successive bends wit...

The effect of a temporal gradient in shear and steady shear on the activity of extracellular signal-regulated protein kinases 1 and 2 (ERK1/ERK2), c-fos, and connexin43 (Cx43) in human endothelial cells was investigated. Three laminar flow profiles (16 dyn/cm(2)), including impulse flow (shear stress abruptly applied for 3 s), ramp flow (shear stress smoothly transitioned at flow onset), and st...

Synovial joints are loaded by weight bearing, stretching, and fluid-driven shear. To simulate in vitro fluid-driven shear, we developed an "oscillating Couette flow mechanical shear loader". Oscillating Couette flow mimics relative motion of articular surfaces; hence, characterizing flow-induced shear by the loader enhances understanding of mechanotransduction in the joint tissue. Here, the ana...

The mechanism of internal transport barrier (ITB) collapse in the reversed magnetic shear configuration is investigated using a global Ion Temperature Gradient driven drift wave (ITG) turbulence code. The heating source and the Toroidal Momentum Source (TMS) is introduced to follow the selfconsistent evolution of the ion temperature and flow profiles. The Toroidal Flow Shear (TFS) effect on the...

The formation of internal transport barriers (ITBs) is investigated in MAST spherical tokamak (ST) plasmas. The roles of E×B flow shear, q-profile (magnetic shear) and MHD activity in their formation and evolution are studied using data from high-resolution kineticand q-profile diagnostics. In L-mode plasmas, with co-current directed NBI heating, ITBs in the momentum and ion thermal channels fo...

Fluid shear stress has profound effects on cell physiology. Here we present a versatile microfluidic method capable of generating variable magnitudes, gradients, and different modes of shear flow, to study sensory and force transduction mechanisms in cells. The chip allows cell culture under spatially resolved shear flow conditions as well as study of cell response to shear flow in real-time. U...

Endothelial cells are constantly exposed to fluid shear stresses that regulate vascular morphogenesis, homeostasis, and disease. The mechanical responses of endothelial cells to relatively high shear flow such as that characteristic of arterial circulation has been extensively studied. Much less is known about the responses of endothelial cells to slow shear flow such as that characteristic of ...

Following recent works of several authors like Huilgol, Bhattacharya etd. and Javadpour et al., this paper is to contribute further to the literature of axial flow in a rotational coaxial rheometer. We consider axial flow of Herschel Bulkley mode1 between two concentric cylinders with the inner one rotating, while the outer cylinder is held stationary. An attempt has been made to direct the...