This research has been conducted on tea grown in the western Mediterranean region and also consumption of Sideritis stricta condensate species, order to investigate their antimicrobial activity against 6 pathogenic bacteria. The plants were collected dried at room temperature flowering stage. essential oil was obtained with a Clevenger apparatus by hydrodistillation method. Antibacterial activi...

From the overground parts of an endemic Sideritis species, S. stricta, 4 diterpenes, sideridiol (1), isosidol (2), isolinearol (3), and linearol (4); 2 flavonoid glycosides, isoscutellarein 7-O-[6′′′-O-acetyl-β-Dallopyranosyl-(1→2)]-β-D-glucopyranoside (5), and isoscutellarein 7-O-[6′′′-O-acetyl-β-D-allopyranosyl(1→2)]-6′′-O-acetyl-β-D-glucopyranoside (6); a methoxyflavone, xanthomicrol (7); an...

SCOPE GABAA receptors are modulated by Sideritis extracts. The aim of this study was to identify single substances from Sideritis extracts responsible for GABAA receptor modulation. METHODS AND RESULTS Single volatile substances identified by GC have been tested in two expression systems, Xenopus oocytes and human embryonic kidney cells. Some of these substances, especially carvacrol, were hi...

A hydroethanolic extract (20% V/V) from Herba Sideritis scardica has been recognized to positively influence cognition. The present investigation aimed at the question if this extract would be able to modify intra-hippocampal communication after oral administration of 100 mg/kg daily for one week. The glutamatergic synapse between Schaffer Collaterals and pyramidal cells can be tested by electr...

The pentacyclic triterpenes rhoiptelenol and rhoiptelenone have been isolated from Sideritis macrostachya. Rhoiptelenone is a new natural compound, whose structure has been determined as D:B-friedo-urs-5-en-3-one. The 1H and 13C NMR spectra of rhoiptelenol, rhoiptelenol acetate and glutinol have been reassigned. The natural occurrence of the D:B-friedo-ursene and D:B-friedo-oleanene derivatives...