antidepressants—specifically clomipramine, fluoxetine, paroxetine, and sertraline—are best and have been shown to improve symptoms of premature ejaculation (strength of recommendation [sor]: a, meta-analysis of randomized controlled trials [rcTs]). The topical application of prilocaine-lidocaine cream (trade name eMla) improves intravaginal ejaculatory latency time (IelT), but penile numbness a...

Objective(s) Sildenafil citrate is a new drug and has special properties that bring about nitric oxide effects on vascular smooth muscle. The aim of this study was to assess the effects of ovarian stimulation and sildenafil citrate injection on pinopode expression in mice. Materials and Methods Thirty adult female mice were randomly divided into three groups: control, hyperstimulated and hyp...

Sildenafil citrate is a commonly used medication for the management of erectile dysfunction. Previous studies have reported psychiatric side effects this medication. So far, there has been paucity literature. We present case 42-year-old male, without known history, who developed psychotic symptoms following initiation sildenafil. also tried postulating mechanism by which may occur. This report ...

Sildenafil can be used for the management of right ventricular failure after left assist device (LVAD) implantation. However, usefulness sildenafil on subpulmonic morphological ventricle (pLV) has not been reported. This study reported haemodynamic effects pLV LVAD

background: pregnancies with early onset fetal growth restriction have poor perinatal outcome. sildenafil citrate (pde -5 inhibitor) as a vasodilator increases uteroplacental blood flow and potentiates fetal growth. case presentation: in this study, a case was examined and sildenafil was administered for her. it was found that sildenafil improved the uterine blood flow with a favorable fetal ou...

background: sildenafil citrate may increase endometrial thickness and affect the outcome of frozen-thawed embryo transfer cycles. objective: the aim of this study was to estimate the effect of sildenafil citrate on ultrasonographic endometrial thickness and pattern and to investigate the estrogen level on the day of progesterone administration, the implantation rate and chemical pregnancy rate ...

BACKGROUND Sildenafil citrate is an effective and widely prescribed therapy for erectile dysfunction. Little is known about the effects of sildenafil on neural control of the circulation or about the effects of sildenafil on neurocirculatory stress responses. METHODS AND RESULTS We studied 14 normal volunteers (age 32+/-7 years) who were randomized in a double-blind crossover fashion to recei...

Background and Aim: Despite the advances in maxillofacial surgery, impaired bone healing remains a concern for surgical teams. Effects of sildenafil and pentoxifylline on healing of bone fractures have not been well investigated. This study aimed to assess the effects of sildenafil and pentoxifylline phosphodiesterase inhibitors on healing of mandibular fractures in rats. Materials and Methods...