Drugs are administered by using different drug delivery systems. A number of drug delivery systems have evolved over the years. In the last 20 years TDDS (Transdermal drug delivery system) has been growing at a rapid pace. Now the micro needles are being developed as a novel drug delivery system. The micro needle skin patch system is also a drug delivery system, which will be used transdermally...

Conventional transdermal drug delivery systems (TDDS) have been designed for drug delivery through the skin. These systems use the permeability property of stratum corneum, the outermost surface layer of the skin. Applying polymeric micro and nanofibers in drug delivery has recently attracted great attention and the electrospinning technique is the preferred method for polymeric micro-nanofiber...

the aim of this work was to study the antimicrobial activity of tomato skin lycopene oleoresin against pseudomonas aeruginosa، escherichia coli، staphylococcus ureuse، salmonella typh ، l. monocytogenes ، bacillus cereus، bacillus licheniformis. oleoresin was extracted from tomato peel. lycopene content was measured by spectrophotometer. lycopene oleoresin contained 2321mg lycopene/ 100 g oleor...

OBJECTIVE Skin autofluorescence is a noninvasive measure of the level of tissue accumulation of advanced glycation end products, representing cumulative glycemic and oxidative stress. Recent studies have already shown a relationship between skin autofluorescence and diabetes complications, as well as the predictive value of skin autofluorescence for total and cardiovascular mortality in type 2 ...

We already reported that genetically engineered resveratrol-enriched rice (RR) showed to down-regulate skin melanogenesis. To be developed to increase the bioactivity of RR using calli from plants, RR was adopted for mass production using plant tissue culture technologies. In addition, high-pressure homogenization (HPH) was used to increase the biocompatibility and penetration of the calli from...

Introduction The skin barrier function is a major challenge for delivery of drugs via the skin. Located in the outermost layer of the skin, the stratum corneum (SC) consists of dead cells embedded in lipid regions, only 10–20 µm thick, tough but flexible and elastic. Hypodermic needles penetrate the skin succesfully, but nerve rich tissue in the lower skin is penetrated which is simply painfull...

In this paper are assumed micro-ridges and micro-grooves on t he journal and bearing sleeve surfaces. Friction on the boundary layer of the body moving in the oil at high Reynolds numbers may be decreased due to su ch a sculpturing of the surface. The grooved scale of the shark skin is an example of such tribological systems. There size ranges of the grooves are from 200 m to 400 m. The surface...