The solubilizing ability of two aromatic hydrotropes, N,N-diethylnicotinamide (DENA) and N,N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally diverse drugs. The number of aromatic rings in the solute molecule has a very strong effect on the solubility enhancement produced by either hydrotrope. However, although solubility enhancements in the order of 100...

An aqueous primary standard is needed for measuring cholesterol by enzymatic procedures. Sodium deoxycholate solubilizes cholesterol in water. Crystalline cholesterol (1.00, 3.00, 4.00, and 5.00 g/L), added to a solution containing 150 g of this compound per liter of a 9 g/L saline solution, was measured by a cholesterol oxidase procedure, with a centrifugal analyzer. The solubilizer did not in...

BACKGROUND Blowflies are economic pests of the wool industry and potential vectors for epidemics. The establishment of a pesticide-free, environmentally friendly blowfly control strategy is necessary. Blowflies must feed on meat in order to initiate the cascade of events that are involved in reproduction including juvenile hormone synthesis, vitellogenesis, and mating. During feeding blowflies ...

The role of soil-borne microalgae in the edaphic ecosystem is barely known, especially concerning their plant-growth-promoting traits, although they are used as biofertilizers. In this study, a microalgal strain isolated from soil cultivated with maize was evaluated an exogenous producer indole-3-acetic acid (IAA) potato dextrose broth—PD—and sugarcane molasses, or without tryptophan, and phosp...

Introduction. LHS-1269 is an indolocarbazole derivative with high antitumor activity. Due to the hydrophobic properties of active substance, use organic co-solvents – dimethyl sulfoxide (DMSO) and ethanol required obtain injectable dosage form (DP). However, inclusion solvents in composition DF carries a potential risk side effects as result drug. Aim. Selection auxiliary substances for obtaini...

Experiments were conducted to evaluate the potential of phosphate solubilizing bacteria (PSB) Bacillus megaterium and potassium solubilizing bacteria (KSB) Bacillus mucilaginosus inoculated in nutrient limited soil planted with eggplant. Results showed that rock P and K materials either applied singly or in combination did not significantly enhance soil availability of P and K. PSB increased hi...