Open burn pits, at times a necessary method to control accumulating waste at military forward operating bases, have been implicated as the cause of respiratory disease and other illnesses. Exposure assessments of open burn pits are often complicated by a lack of sampling equipment and resources. This research investigated the hypothesis of carbon dioxide (CO2) as a viable surrogate for particul...

To understand the role of l-arginine depletion in impaired nitric oxide synthesis in disease, it is important to simultaneously quantify arginine, citrulline, and ornithine in the plasma. Because the three amino acids are endogenous analytes, true blank matrix for them is not available. It is necessary and valuable to compare the performance of different approaches due to lack of regulatory cla...

Nerve agents that irreversibly deactivate the enzyme acetylcholinesterase are extremely toxic weapons of mass destruction. Thus, developing methods to detect these lethal is important. To create an optical sensor for a surrogate nerve agent tabun, as well physical barrier dissolves in response this analyte, we devise network hydrogel decomposes via self-propagating cascade. A Meldrums acid-deri...

the net analyte signal standard addition method was used for simultaneous spectrophotometric determination of sertraline and fluoxetine in pharmaceutical preparations. the method combines the advantages of the standard addition method with the net analyte signal concept to enable the extraction of information about an analyte from the spectra of multi-component mixtures. this method uses full s...

background: using the method “surrogacy” in which a woman accepts to bear and deliver a child for a married couple is considered as a subsidiary method in infertility therapy. this method is relatively new in iran. objective: the purpose of this study was to evaluate the experiences of the women involved in surrogacy and to reveal some issues related to this method. materials and methods: the m...

three antituberculosis medications are investigated in this work consist of rifampicin, isoniazid and pyrazinamide. the ultra violet (uv) spectra of these compounds are overlapped, thus use of suitable chemometric methods are helpful for simultaneous spectrophotometric determination of them. a generalized version of net analyte signal standard addition method (gnassam) was used for determinatio...

There is a clear need for an instrument-free molecular diagnostic system for detecting human immunodeficiency virus type 1 (HIV-1) RNA or DNA that can be used in developing countries. Such a test could be used for early diagnosis of HIV-1 infection during infancy and could serve as a surrogate end point for vaccine trials. We developed the IsoAmp HIV-1 assay (BioHelix Corporation), which target...