We discuss how a theoretical synthetic biology research programme may liberate empiricism in biological sciences beyond the unaided human brain. Because synthetic biological systems are relatively small and largely independent of evolutionary contexts, they can be represented with mathematical models strongly founded on first principles of molecular biology and laws of statistical thermodynamic...

In the process of designing complex chips and systems, the use of benchmark designs is often necessary. However, the existing benchmark suites are not sufficient for the evaluation of new architectures and EDA tools; synthetic benchmark circuits are a viable alternative. In this paper, a systematic approach for the generation and evaluation of synthetic benchmark circuits is presented. A number...

Subdermal contraceptive implants are an additional approach to meeting the world-wide need for more effective and acceptable birth control. They provide long-acting, highly effective and reversible contraception by achieving low and stable concentrations of synthetic progestogens and require little user compliance, thereby achieving user failure rates that are similar to the method failure rate...