24 25 Host pathogen interactions are of great importance in understanding the pathogenesis 26 of infectious microorganisms. We developed in vitro models to study the host-pathogen 27 interactions of porcine respiratory tract pathogens using two immortalized epithelial cell 28 lines, namely the Newborn Pig Trachea (NPTr) and the St. Jude Porcine Lung (SJPL) cell 29 lines. We first studied the in...

24 25 Host pathogen interactions are of great importance in understanding the pathogenesis 26 of infectious microorganisms. We developed in vitro models to study the host-pathogen 27 interactions of porcine respiratory tract pathogens using two immortalized epithelial cell 28 lines, namely the Newborn Pig Trachea (NPTr) and the St. Jude Porcine Lung (SJPL) cell 29 lines. We first studied the in...

24 25 Host pathogen interactions are of great importance in understanding the pathogenesis 26 of infectious microorganisms. We developed in vitro models to study the host-pathogen 27 interactions of porcine respiratory tract pathogens using two immortalized epithelial cell 28 lines, namely the Newborn Pig Trachea (NPTr) and the St. Jude Porcine Lung (SJPL) cell 29 lines. We first studied the in...

Host-pathogen interactions are of great importance in understanding the pathogenesis of infectious microorganisms. We developed in vitro models to study the host-pathogen interactions of porcine respiratory tract pathogens using two immortalized epithelial cell lines, namely, the newborn pig trachea (NPTr) and St. Jude porcine lung (SJPL) cell lines. We first studied the interactions of Actinob...

•Syn3B can form antibiotic tolerant and persister subpopulations with only 473 genes•Syn3B evolves expeditiously to gain resistance against multiple antibiotics•Syn3B contains a few systems previously linked persistence (e.g., protease)•Syn3B lacks ribosome dimerization) Antibiotic is growing problem, but bacteria evade treatment via tolerance persistence. persisters are small subpopulation of ...