To study the assembly of gap junctions, connexin--green-fluorescent-protein (Cx--GFP) chimeras were expressed in COS-7 and HeLa cells. Cx26-- and Cx32--GFP were targeted to gap junctions where they formed functional channels that transferred Lucifer Yellow. A series of Cx32--GFP chimeras, truncated from the C-terminal cytoplasmic tail, were studied to identify amino acid sequences governing tar...

We address existence of moving gap solitons (traveling localized solutions) in the Gross-Pitaevskii equation with a small periodic potential. Moving gap solitons are approximated by the explicit localized solutions of the coupled-mode system. We show however that exponentially decaying traveling solutions of the Gross-Pitaevskii equation do not generally exist in the presence of a periodic pote...

We show that in ultrasmall superconducting grains any concentration of magnetic impurities or infinitely small orbital effect of magnetic field leads to destruction of the hard gap in the tunneling density of states, and find analytically the exponential tail at low energies. Thus, the tunneling density of states exhibits the "soft gap" behavior. As the energy approaches zero, it vanishes linea...

Gap genes encode transcription factors involved in the patterning of the head-tail axis of insect embryos. In this issue of Cell, Savard et al. (2006) identify a beetle gap gene, mille-pattes, that encodes an unusual polycistronic transcript predicted to produce four conserved peptides. These results have interesting implications for the control of embryonic patterning in insects.

Abstract Tuberous sclerosis complex (TSC) integrates upstream stimuli and regulates cell growth by controlling the activity of mTORC1. TSC functions as a GTPase-activating protein (GAP) towards small GTPase Rheb inhibits Rheb-mediated activation Mutations in genes cause tuberous sclerosis. In this study, near-atomic resolution structure human reveals an arch-shaped architecture, with 2:2:1 stoi...

This study analyzed the transformer electromagnetic gap propagation characteristics. The influence of gap size is also analyzed, and the results experimentally verified. The obtained results indicated that the gap propagation characteristics of electromagnetic wave signals radiated by the partial discharge (PD) source in different directions are substantially different. The intensity of the ele...

CP measurements show that PBTI stress induced interface trap area density ΔNit in InGaAs/Al2O3 n-MOSFET is very small and has power law time evolution At in the stress phase, and is partially recovered in the recovery phase. However the DC Is-Vg measurements show large degradations of negative ΔVg and sub-threshold swing S in the sub-threshold region and are recovered in the recovery phase, als...

In the Drosophila embryo, pecif1cation of terminal cell fates that result in the formation of both the head (acron) .and tail (telson) regions is under the control of the torso (tor) receptor tyrosine kinase. The current knowledge suggests that activation of tor at the egg pole initiates a signal transduction pathway that is mediated sequentially by the guanine nucleotide releasing factor son o...