OBJECTIVE(S) This study aimed to find out whether the chick cardiomyocyte micromass (MM) system could be employed to predict the teratogenecity of common environmental factors. Different multivitamins and over the counter drugs were used in this study. MATERIALS AND METHODS White Leghorn 5-day-old embryo hearts were dissected and trypsinized to produce a cardiomyocyte cell suspension in Dulbe...

Contaminated water is the primary source of any disease. Water may be contaminated by number of pollutants and dyes are one of them. Malachite green (MG) dye is widely used as biocide in the aquaculture industry to controls fungal attacks, protozoan infections and also used in food and textile industries for various purposes. Surface and ground water is contaminated with dyes due to discharge o...

Reactive oxygen species (ROS) are involved in physiological functions and act as mediators in various signaling processes. Elevated or sustained generation of free radicals and non radical species derived from free radicals can lead to an imbalance in the intracellular redox homeostasis. Normally, any excess levels of reactive radical and nonradical species generated are intercepted by antioxid...

The term “limb deficiency” incorporates absence and/or size reduction of any of the 120 human limb bones, with around 205 identified nosologic entities. Of these, the GollopWolfgang Complex (GWC) is a rare abnormality comprising absence of tibia and ipsilateral forked femur with ectrodactyly. There is scarcity of literature implicating antiepileptic drugs in the etiology of GWC but the teratoge...

The increasing uses of zinc oxide nanoparticles (nZnO) in industrial and personal care products raise possible danger of using nZnO in human. To determine whether ZnO induces size-dependent anomalies during embryonic organogenesis, mouse embryos on embryonic day 8.5 were cultured for 2 days under 50, 100, and 150 μg of nZnO (< 100 nm) or micro-sized ZnO (mZnO; 80 ± 25 μm), after which the morph...

Reactive oxygen species (ROS) are involved in physiological functions and act as mediators in various signaling processes. Elevated or sustained generation of free radicals and non radical species derived from free radicals can lead to an imbalance in the intracellular redox homeostasis. Normally, any excess levels of reactive radical and nonradical species generated are intercepted by antioxid...

  Objective(s): This study aimed to find out whether the chick cardiomyocyte micromass (MM) system could be employed to predict the teratogenecity of common environmental factors. Different multivitamins and over the counter drugs were used in this study.   Materials and Methods: White Leghorn 5-day-old embryo hearts were dissected and trypsinized to produce a cardiomyocyte cell suspension in D...

OBJECTIVE Methoxsalen is a natural photoactive compound which is found in many seed plants. A number of epidermal proliferative disorders can be treated by methoxsalen along with long wave ultraviolet A (UVA). MATERIALS AND METHODS In an experimental study, we aimed to demonstrate the effect of methoxsalen, UVA and their combination on oogenesis Balb/C mice. There were two experimental groups...

objective(s): this study aimed to find out whether the chick cardiomyocyte micromass (mm) system could be employed to predict the teratogenecity of common environmental factors. different multivitamins and over the counter drugs were used in this study.   materials and methods: white leghorn 5-day-old embryo hearts were dissected and trypsinized to produce a cardiomyocyte cell suspension in dul...