We report on the synthesis of a novel class functionalized thia[6]helicenes and thia[5]helicene, containing benzothiophene unit second heteroatom embedded in helix (i.e., nitrogen oxygen) or pyrene spirobifluorene moiety. These systems are obtained through straightforward general procedures that involve: (i) palladium-catalyzed annulation iodo-atropoisomers with internal alkynes (ii) Suzuki cou...

Introduction: [18F]-6-thia-14-fluoro-heptadecanoic acid 3b, a free fatty acid, has been used in myocardial PET imaging. In order to establish an automated synthesis module for routine production in the country, a study performed for optimization of the production conditions as well as making modifications. Methods: [18F] Benzyl-14-Fluoro-6-thia-heptadecanoate 2b was prepared in no-carrier...

Three ring-substituted 3-aryl analogs of 2-phenyl-2,3-di-hydro-4H-1,3-benzo-thia-zin-4-one, namely 3-(4-meth-oxy-phen-yl)-2-phenyl-4H-1,3-benzo-thia-zin-4-one, C21H17NO2S, (I), 2-phenyl-3-[4-(tri-fluoro-meth-yl)phen-yl]-2,3-di-hydro-4H-1,3-benzo-thia-zin-4-one toluene hemisolvate, C21H14F3NOS·0.5C7H8, (II), and 3-(3-bromo-phen-yl)-2-phenyl-2,3-di-hydro-4H-1,3-benzo-thia-zin-4-one toluene hemiso...

In the title mol-ecule, C(15)H(10)BrNO(4)S, the heterocyclic thia-zine ring adopts a half-chair conformation, with the S and N atoms displaced by 0.554 (7) and 0.198 (8) Å, respectively, on opposite sides of the mean plane formed by the remaining ring atoms. The mol-ecular structure is consolidated by intra-molecular O-H⋯O inter-actions and the crystal packing features N-H⋯O and C-H⋯O hydrogen ...

In the title compound, C(25)H(21)NO(7)S, the heterocyclic thia-zine ring adopts a half-chair conformation, with the S and N atoms displaced by -0.284 (3) and 0.411 (3) Å, respectively, from the plane formed by the remaining ring atoms; the puckering parameters are: Q = 0.4576 (13) Å, θ = 58.6 (2) and ϕ = 34.3 (3)°. The structure is devoid of any classical hydrogen bonds. However, intra-molecula...

The title compound, C(12)H(12)ClN(3)S, features a thia-zolyl ring having an envelope conformation with the -CH(2)- group bonded to the S atom forming the flap. The C=N double bond has a Z configuration. The crystal structure shows inter-molecular C-H⋯S hydrogen bonds.

The Long-Term Hydrology Impact Assessment (L-THIA) model has been used as a screening evaluation tool in assessing not only urbanization, but also land-use changes on hydrology in many countries. However, L-THIA has limitations due to the number of available land-use data that can represent a watershed and the land surface complexity causing uncertainties in manually calibrating various input p...

2,5-Bis(pyridin-2-yl)-1,3,4-thia-diazole (denoted L) has been found to act as a bidentate ligand in the monomeric title complex, [Cu(CF(3)O(3)S)(C(12)H(8)N(4)S)(2)(H(2)O)](CF(3)O(3)S). The complex shows a distorted octahedrally coordinated copper(II) cation which is linked to two thia-diazole ligands, one water mol-ecule and one trifluoro-methane-sulfonate anion. The second trifluoro-methane-su...

In the crystal structure of the title compound, C7H5NO4·C9H9N3O2S2, the sulfa-thia-zole and 4-nitro-benzoic acid mol-ecules are held together by short π-π contacts between the thia-zole and nitro-benzene rings, with a centroid-centroid distance of 3.8226 (7) Å. The sulfa-thia-zole mol-ecules form dimers via N-H⋯N hydrogen bonds involving the thia-zole and sulfonamide moieties, owing to the fact...