Effects of antidepressant drugs on the amygdaloid after-discharge induced by stimulating the amygdala in rats implanted with chronic electrodes, were investigated in correlation with anti-muricidal effects as well as neurotoxicity. Tricyclic antidepressants such as amitriptyline, imipramine and nortriptyline markedly depressed both after-discharge and muricide at doses smaller than neurotoxic d...

Depending upon whom you heed and what you read, benzodiazepines are either the safest and most useful anxiety relieving drugs so far discovered, or among the more potentially harmful addictive substances. According to their detractors (Lader, 1978; Marks, 1978) benzodiazepines have become increasingly popular because of medical indiscretions and over vigorous advertising. Drugs are neither inhe...

The study on the perception of 264 (33.2%) nursing students from the Professionalization and Regular groups regarding predicting factors of drugs consumption shows these students consume alcohol and tobacco and view alcohol as a leading factor in the consumption of drugs. The Professionalization group consumes tranquilizers and stimulants at a higher rate than the Regular group. The Professiona...

PURPOSE To determine the social contexts associated with the past-year substance use (multiple substances, alcohol, marijuana, and nonmedical use of prescription opioids, stimulants, and tranquilizers) among U.S. high school seniors. METHODS A secondary analysis of nationally representative survey data from 10 cohorts (2002-2011) of the Monitoring the Future study, including 24,809 high schoo...

The nonmedical use of scheduled medications commonly prescribed for pain, pain-related symptoms, and psychiatric disorders began rising in the mid-1990s. Physicians are confronted with the dilemma of how to minimize the abuse and diversion potential of these products without compromising access for patients with a legitimate medical need. Using data from the National Survey on Drug Use and Heal...

Background: Substance abuse is one of the main health problems in Iran and awareness about its spread and procedure of spread in the society, particularly the susceptible society of students, is very important with regard to the population pyramid of Iran. Methods: This study was performed by cross-sectional method. The sampling size was 610 male students in pre-university grade by a probabilis...