What is translational medicine? This question has been vigorously debated by various constituencies for many years. One recent, encompassing definition of translational medicine was developed for the Strategic Plan in service of the American Society for Clinical Pharmacology and Therapeutics (ASCPT).1,2 Not coincidentally, the ASCPT Strategic Plan was aptly entitled “Transforming Translation.”

Widespread use of microarray technology that led to highly complex datasets often is addressing similar or related biological questions. In translational medicine research is often based on measurements that have been obtained at different points in time. However, the researcher looks at them as a progression over time. If a biological stimulus shows an effect on a particular gene that is rever...

Translational research plays a crucial role in bridging the gap between fundamental and clinical research. The importance of integrating research training into medical education has been emphasized. Predictive factors that help to identify the most motivated medical students to perform academic research are unknown. In a cross-sectional study on a representative sample of 315 medical students, ...

In order to enhance biomedical research and development efficiency and innovation, nontraditional research collaborations have emerged that feature the sharing of information, resources, and capabilities. Although many of these so-called precompetitive collaborations are in the field of oncology, the lessons they offer are broadly applicable to other subfields of translational medicine.

Editor’s Note: In 2003, the Society for Neuroscience initiated the Science Educator Award to recognize an outstanding neuroscientist who has made significant contributions to the education of the public (http://www.sfn.org/content/Programs/AwardsandPrizes/sea.html). The first recipient was Eric Chudler, PhD, at the University of Washington. For more on his activities, see http://faculty.washing...

The inclusion of engineering ideas and approaches makes medicine a quantitative and systems-based discipline that facilitates precision diagnostics and therapeutics to improve health care delivery for all.

Elaine Mardis and Marc Ladanyi discuss how large-scale genomics has driven advances in cancer translational medicine, with a focus on publications in this month's Special Issue.

B. R. Pitt, J. W. Christman, S. J. Gunst, M. A. Matthay, T. Stevens, and L. B. Ware Department Environmental and Occupational Health, University of Pittsburgh Graduate School Public Health, Pittsburgh, Pennsylvania; Section of Pulmonary Medicine, Critical Care and Sleep Medicine, Department of Medicine, University of Illinois, Chicago, Illinois; Department Cellular and Integrative Physiology, I...

Graduate-level education in translational medicine will require more than just scientific research.