conclusions anti-tuberculosis drugs-induced hepatotoxicity caused treatment interruption in 5.5% of the patients with tuberculosis. the majority of the patients with dih were above fifty, and 50% the cases occurred during the first two weeks after treatment onset. physicians must carefully and closely monitor such patients. background hepatotoxicity is one of the most frequent adverse events th...

background: tuberculosis remains a worldwide public health problem and india accounts for highest tb burden in the world. the aim of the study was to evaluate the trend and treatment outcome of tuberculosis (tb) cases treated under dots strat­egy at a district level in karnataka, india. methods : this was a retrospective record based study conducted in dakshina kannada district of karnataka, du...

global tuberculosis (tb) report (2013) has revealed that an estimated 8.6 million people developed tb of which, india accounts for almost 26% of the cases. these estimates clearly suggest that the country’s efforts to achieve millennium development goal 6 by 2015 have not delivered the desired output. in india, the tb prevention and control activities are supervised and implemented under the re...

extensively drug-resistant tuberculosis (xdr-tb) is a new challenge for tuberculosis control programs. lack of effective drugs and high rate of failure in treatment and mortality is a major threat for public health. treatment of this serious infection needs well-designed individualized dosage regimen and powerful national tb program. in this review we will describe the xdr-tb definition and its...

A retrospective study of 300 tuberculosis patients on short course chemotherapy registered in 1985 at the Chest Clinic, General Hospital Alor Setar, Kedah was carried out with the purpose of identifying patient characteristics, determining incidence of side-effects and modifying treatment regimens in order to minimise these side-effects. One hundred and sixteen (38.7%) patients developed side e...