BACKGROUND The increasing number of patients with chronic diseases represents a challenge for health care systems. The Chronic Care Model suggests a multi-component remodelling of chronic disease services to improve patient outcomes. To meet the complex and ongoing needs of patients, chronic disease prevention and management (CDPM) has been advocated as a key feature of primary care producing b...

Most clustering algorithms assume that all dimensions of the data can be described by a single structure. Cross-clustering (or multiview clustering) allows multiple structures, each applying to a subset of the dimensions. We present a novel approach to crossclustering, based on approximating the solution to a Cross Dirichlet Process mixture (CDPM) model [Shafto et al., 2006, Mansinghka et al., ...

The human respiratory system is the gateway of entry for inhaled detritus from anthropogenic (e.g. combustionderived (CD) particulate matter (PM; e.g. diesel exhaust and wood-burning PM). Adult humans inhale 20m 3 of air and suspended debris (gases and particles) into the airways daily. Inhalation exposure to CDPM (Figure 1) is known to increase the risk of morbidity and mortality of lung and h...

BACKGROUND Chronic alcohol consumption causes persistent oxidative stress in the lung, leading to impaired alveolar macrophage (AM) function and impaired immune responses. AMs play a critical role in protecting the lung from particulate matter (PM) inhalation by removing particulates from the airway and secreting factors which mediate airway repair. We hypothesized AM dysfunction caused by chro...

In this paper, a markovian queue with two types of servers and buffer space is considered. The resequencing constraint is imposed according to which the customers leave the system in the same order in which they entered it. For finite buffer queue, the steady state queue size distribution has been obtained.?