Telah dikemukakan bahwa virus corona menjadi penyebab COVID-19.(1) Virus yang dimaksud yaitu SARS-CoV-2, sedangkan COVID-19 kependekan dari disease-19. adalah penyakit disebabkan oleh SARS-CoV2 muncul awal Desember tahun 2019 di Wuhan, China. Sifat tersebut mudah menginfeksi manusia dan menyebar hampir keseluruh penjuru dunia. Oleh karena itu terjadilah wabah (pandemi) COVID-19.
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The aim of the present study was to detect polymorphism in Insulin like growth factor-I (IGF-I) gene of beluga (Huso huso) fish using PCR-SSCP technique and also investigation of its association with growth traits (condition factor, body length and weight). A total of 150 specimens of beluga were randomly selected and DNA was isolated from caudal fin using modified salting out method. Then two ...

Our knowledge of the evolution and role untranslated region (UTR) in SARS-CoV-2 pathogenicity is very limited. Leader sequence, originated from UTR, found at 5? ends all encoded transcripts, highlighting its importance. Here, leader sequence was compared between human pathogenic non-pathogenic coronaviruses. Then, profiling microRNAs that can inactivate key UTR regions coronaviruses carried out...

uterine infection is one of the reproductive diseases that can have disturbing postpartumuterine health in cattle. therefore, identification of resistant genotypes to uterine infection isimportant. lactoferrin (lf) is one of the major antimicrobial compounds in the normal uterinedischarges of cows. we hypothesized that allelic diversity in lf gene may contribute tosusceptibility or resistance t...

rapid detection and differentiation of infectious bronchitis virus (ibv) involved in the disease outbreak is very important for controlling disease and developing new vaccines. in the present study, three regions of the genome of ibv vaccine and field isolates including s1 gene, gene 3 and nucleocapsid (n) gene along with 3' untranslated region (3' utr) were amplified and subjected to restricti...

The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in cancer invasion and acceptance of allografts. The 5' and 3' regulatory regions of the HLA-G gene are polymorphic and balancing selection probably maintains this variability. It is proposed that nucleotide variations may affect the level of HLA-G expression. To investigate this issue we aimed to analyze how h...

hla-g is a non-classical hla class ib molecule with limited protein variability generated by  alternative  splicing.  hla-g   displays  immunotolerant   properties  and  hence  plays important roles in the maintenance of a successful pregnancy and maternal tolerance of the semiallogenic fetus. polymorphism of the hla-g gene may potentially affect the biological properties of the protein, and a ...