OBJECTIVE To develop a simple summary risk score for the prediction of Alzheimer disease in elderly persons based on their vascular risk profiles. DESIGN A longitudinal, community-based study. SETTING New York, New York. Patients One thousand fifty-one Medicare recipients aged 65 years or older and residing in New York who were free of dementia or cognitive impairment at baseline. MAIN OU...

BACKGROUND Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA. We assessed the value of this score to predict the vascular outcome after TIA during medium- to long-term follow-up. METHODS The ABCD2 score of 176 TIA patients consecutively admitted to the Stroke Unit was retrospectively cal...

o bjective: to determine the etiology, signs and symptoms, angiography indications and angiography findings in patients with limb penetrating injuries suspected to have arterial injury. m e thods: this was a cross-sectional study being performed in imam reza hospital affiliated with mashhad university of medical sciences, iran between september 2011 and march 2013. we included those patients wi...

BACKGROUND We evaluated prevalence and correlates of increased high-sensitivity C-reactive protein (hsCRP) in a large population of blacks and whites, and the impact of hsCRP measurement on coronary heart disease risk reclassification. METHODS We studied 19 080 participants of the REGARDS (REasons for Geographic And Racial Differences in Stroke) study (age >45 years, without vascular diagnose...

BACKGROUND Genetic studies have identified 2 single-nucleotide polymorphisms (SNPs) at the LPA locus (rs3798220 and rs10455872) that are strongly and independently related to lipoprotein(a) levels and to coronary disease risk, but their relevance for other atherothrombotic disease is uncertain. METHODS AND RESULTS These 2 LPA SNPs were examined together as an LPA genotype score for associatio...

OBJECTIVES We investigated whether the POSSUM physiology score, originally designed as an indicator for 30-day mortality for comparative audit, could be used as an indicator of long-term survival in vascular surgery practice. METHODS Data from 184 different vascular procedures conducted between 1989 and 2000, containing survival data for each patient of 10 years or longer, were analysed retro...