background previous studies using pegylated interferon (peg-ifn) and ribavirin (rbv) combination therapy suggested that patients with hepatitis c virus (hcv) genotype 1 and low pretreatment hcv rna level who achieved rapid virological response (rvr) can be treated for 24 weeks without compromising sustained virological response (svr) rate. objectives the current study aimed to investigate the e...

conclusions the viral load in patients who suffer from cchf has a direct significant correlation with disease severity. viral load above 8.6 × 105 copies/ml on the first day of admission is a predictor of severe cchf. background crimean-congo hemorrhagic fever (cchf) is an endemic disease in south eastern of iran, especially in sistan and baluchestan province. cchf is a potentially fatal diseas...

accurate and rapid diagnosis of human cytomegalovirus (hcmv) disease in immunocompromised patients has remained as a challenge. quantitative competitive pcr (qc-pcr) methods for detection of hcmv in these individuals have improved the positive and negative predictive values of pcr for diagnosis of hcmv disease. in this study we used qc-pcr assay, using a co-amplified dna standard, to quantitate...

background autoimmune hemolytic anemia is a hematologic disorder that is rarely observed in infants and young children. most of the cases are associated with viral or bacterial infections. in some cases, aiha can be characterized by a chronic course and an unsatisfactory control of hemolysis, thus requiring prolonged immunosuppressive therapy. case report especially in children younger than 2 y...

Background: Serial measurement of  hepatitis B virus (HBV) DNA levels in the liver and its relation with liver damage and serum HBV DNA levels are guide to begin and/or end a treatment course. This study evaluated the relationship between liver hepatitis B DNA viral load with liver histology in patients with chronic hepatitis B (HBV). Methods:  Thirty patients with chronic anti-Hbe positive ...

Background: Viral load and alanine aminotransferase (ALT) levels may not be the key points for making a decision in the treatment of anti-HBe positive chronic hepatitis B. The purpose of this study was to assess the histological evaluation of liver to find the need for treatment on 72 patients with anti-HBe positive chronic hepatitis B. Methods: The liver biopsy slides of the 72 patients (56 s...

aim : this study aims to employ random effect model to evaluate prognostic factors of hepatitis c. background : in recent years, hepatitis c virus (hcv) infection has been a major cause of liver diseases worldwide and represents a major public health problem. evaluation of risk factors and a community intervention in order to decrease the problem is one of the solutions which help protect peopl...

understanding of the natural history of chronic hbv infection is useful for presenting the optimal management of chronic hbv infection. the aim of this study was to evaluate the natural history of chronic hepatitis b infection.in this cross sectional study, 219 untreated chronic hepatitis b patients from jan. 2010 to aug. 2012 were included. the subjects were classified in four groups based on ...