This paper is an introductory guide to many-particle hydrodynamic interactions. Basic concepts of the fluid mechanics are assumed to be known. Experience in the Stokes equations is useful but not necessary. The study is estimated to fit five sessions about three hours each. Auguste Rodin: “Nothing else that I have done satisfies me as much, because nothing else cost me so much effort...”[**]

Angelmarin (1), a novel anti-cancer agent, was efficiently synthesized through a highly enantioselective epoxidation and a copper cyanide-mediated esterification of the hindered alcohol as the key steps in 53% overall yield.

The diversely functionalized tricyclic tetrazoles were synthesised from readily available substrates via intramolecular 1,3-dipolar cycloaddition as the key step in good yields (53-78% yield for two steps) with high enantioselectivities (81-99% ee).

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How the remobilization of S and N reserves can meet the needs of seeds of oilseed rape subject to limitation of S fertilization remains largely unclear. Thus, this survey aims to determine the incidence of sulphate restriction [low S (LS)] applied at bolting [growth stage (GS) 32], visible bud (GS 53), and start of pod filling (GS 70) on source-sink relationships for S and N, and on the dynamic...

Long-chain acyl-CoA esters are key metabolites in lipid synthesis and beta-oxidation but, at the same time, are important regulators of intermediate metabolism, insulin secretion, vesicular trafficking and gene expression. Key tools in studying the regulatory functions of acyl-CoA esters are reliable methods for the determination of free acyl-CoA concentrations. No such method is presently avai...

The accelerating trend toward Faster, Better, Cheaper (FEE) missions places increasing emphas is on the trade-offs between requirements and risk to reduce cost and development times, while still improving quality and reliability. The Risk/Requirenlents Trade-off Guidelines discussed in this paper are part of an integrated approach to address the main issues by focusing on the sum of prevention,...