نتایج جستجو برای: β hematin formation

تعداد نتایج: 694399  

2012
Shu-Yu Wu Jimann Shin Diane S. Sepich Lilianna Solnica-Krezel

Embryonic axis formation in vertebrates is initiated by the establishment of the dorsal Nieuwkoop blastula organizer, marked by the nuclear accumulation of maternal β-catenin, a transcriptional effector of canonical Wnt signaling. Known regulators of axis specification include the canonical Wnt pathway components that positively or negatively affect β-catenin. An involvement of G-protein couple...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سمنان - دانشکده گردشگری 1393

در سال¬های اخیر، نگرانی¬های فزاینده¬ی زیست محیطی سبب شده است تا توجه به اکوتوریسم به عنوان نوعی از گردشگری پایدار فزونی یابد. طرح¬های حفاظتی راهی برای توسعه¬ی اکوتوریسم در بسیاری از جوامع در حال توسعه برای رسیدن به پایداری در حال پیگیری است. این طرح¬ها می¬توانند شامل برنامه¬هایی برای توانمندکردن جامعه¬ی محلی به خصوص زنان باشند، چرا که اکوتوریسم پتانسیل زیادی برای توانمندکردن و ایجاد رفاه برای ج...

2001
Louis J. Ignarro

A kinetic characterization of the regulation of purified soluble guanylate cyclase from bovine lung by protoporphyrin M and hematin is reported. Purified guanylate cyclase was isolated with heme and had specific activities @mol of cGMP/min/mg of protein) of 0.1-0.2 and 0.3-0.6 in the presence of excess MgGTP and MnGTP, respectively, in the absence of added activators. Protoporphyrin IX, nitric ...

Journal: :iranian journal of pharmaceutical research 0
mohammad hossein morowvat department of pharmaceutical biotechnology, faculty of pharmacy, shahid beheshti university of medical sciences, valiollah babaeipour biochemical engineering group, biotechnology research center, malek-ashtar university of technology hamid rajabi-memari center of biotechnology and life sciences, shahid chamran university of ahvaz hossein vahidi department of pharmaceutical biotechnology, faculty of pharmacy, shahid beheshti university of medical sciences nader maghsoudi neuroscience research center, shahid beheshti university of medical science

human interferon β (inf-β) is a member of cytokines family which different studies have shown its immunomodulatory and antiviral activities. in this study an expression vector was designed and constructed for expression of human inf-β-1b either in shake flasks and bench top bioreactor. the designed vector was constructed based upon pet-25b(+) with t7 promoter. recombinant human beta interferon ...

Journal: :Journal of medicinal chemistry 2005
Onyeka Onyeibor Simon L Croft Hilary I Dodson Mohammad Feiz-Haddad Howard Kendrick Nicola J Millington Silvia Parapini Roger M Phillips Scott Seville Steven D Shnyder Donatella Taramelli Colin W Wright

A series of analogues of cryptolepine (1) have been synthesized and evaluated for their in vitro antiplasmodial and cytotoxic properties. The IC(50) values of several compounds (11a, 11k-m, 11o, 13) against Plasmodium falciparum (strain K1) were <0.1 muM, 5-10-fold lower than that of 1 but their cytotoxicities were only 2-4 times greater than that of 1. Compounds with a halogen in the quinoline...

Journal: :avicenna journal of medical biotechnology 0

background: protein aggregation is one of the important, common and troubling problems in biotechnology, pharmaceutical industries and amyloid-related disorders. methods: in the present study, the inhibitory effects of some carbohydrates (alginate, β-cyclodextrin and trehalose) on the formation of nano-globular aggregates from normal (hsa) and glycated (ghsa) human serum albumin were studied; w...

Farzad Rajaei, Mohammadali Shokrgozar, Zohreh Bagher,

Background: Bone tissue engineering requires materials that are biocompatible, mechanically suited for bone function, integrated with the host skeleton, and support osteoinduction of the implanted cells for new bone formation. The aim of this study was to compare the osteogenic potential of xenograft with hydroxyapatite/β- tricalcium phosphate (HA/β-TCP) scaffold. Methods: New Zealand rabbits (...

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