BACKGROUND Celiac disease (CD) is a chronic, small intestinal inflammatory disease mediated by dietary gluten and related prolamins. The only current therapeutic option is maintenance of a strict life-long gluten-free diet, which implies substantial burden for CD patients. Different treatment regimes might be feasible, including masking of toxic celiac peptides with blocking antibodies or fragm...

Incomplete Freund's adjuvant (IFA) is used as standard adjuvant for the production of specific antibodies. In this study, we evaluated the ability of supplementation of IFA with 1alpha,25-dihydroxyvitamin D(3) [1alpha,25(OH)(2)D(3)] or C-phosphate-guanosine-oligodeoxynucleotide (CpG-ODN) to enhance the quantity of specific IgY found in the eggs of hyperimmunized laying hens. In this comparative...

The aim of this study was the production of specific IgY against cell-associated, highly conserved mammalian proteins. CD 14 is expressed on monocyte surfaces and was identified as endotoxin receptor. P 23 is a cellular protein with unclear biological function. The induction, preparation and characterization of egg yolk antibodies against these antigens are described.

BACKGROUND Campylobacter jejuni is a major cause of foodborne disease having chickens as an important reservoir. Its control at the farm would lower the contamination of the final products and therefore also lower the risk of transmission to humans. At the farm, C. jejuni is rarely found in chickens before they reach 2 weeks of age. Past studies have shown that maternal antibodies could hamper ...

Hens (White Leghorn) were immunized with different protein antigens and antibodies were isolated from eggs by PEG precipitation. To determine experimental conditions under which optimal antibody titers are reached the antigen dose and the mode of application were varied. Injecting the antigen three times every four weeks in the absence of adjuvant led to a phase like immune response. A plateau ...

The present paper describes the methods for producing egg yolk antibodies against Bordetella bronchiseptica. In comparative experiments, avian and mammalian antibodies were applicated in diagnostic test systems. The results of these investigations show the possibility of substituting mammalian antibodies for IgY in enzyme immunoassay and indirect immunofluorescence.

Solar Cycle 19 was probably the greatest solar cycle over last four centuries and significantly disrupted solar-terrestrial environments with a number of eruptions resultant geomagnetic storms. At its peak, International Geophysical Year (IGY: 1957 -- 1958) organised by international collaborations benefitted scientific developments, capturing multiple unique extreme space weather events includ...