This study aimed to evaluate plasma concentration of selected cancer-associated inflammatory and immune-modulated cytokines in HIV+ patients with advanced Kaposi sarcoma (KS), and to explore candidate biomarkers capable of predicting clinical outcome in response to chemotherapy (CT) plus combination antiretroviral therapy (cART).Thirty-seven plasma cytokines/chemokines were assessed by Luminex ...

Data mining technology is applied to extract the water supply operation rules in this study. Five characteristic attributes—reservoir storage water, operation period number, water demand, runoff, and hydrological year—are chosen as the dataset, and these characteristic attributes are applied to build a mapping relation with the optimal operation mode calculated by dynamic programming (DP). A Le...

BACKGROUND In treatment of human immunodeficiency virus (HIV), high levels of adherence to combination antiretroviral therapy (cART) are required to prevent failure of virologic suppression, development of drug resistance, and permanent loss of therapeutic options. No published research has assessed the association between cART prescription cost sharing and adherence to cART. OBJECTIVE To ana...

PURPOSE OF REVIEW In general, the initiation of combination antiretroviral (cART) is associated with improvement in cognitive function. However, the impact of cART has on cognitive function in neurologically asymptomatic HIV-infected individuals initiating therapy at high CD4 lymphocyte cell counts is unknown. RECENT FINDINGS Cognitive function impairment remains prevalent despite effective c...

BACKGROUND Classification and regression tree (CART) models are tree-based exploratory data analysis methods which have been shown to be very useful in identifying and estimating complex hierarchical relationships in ecological and medical contexts. In this paper, a Bayesian CART model is described and applied to the problem of modelling the cryptosporidiosis infection in Queensland, Australia....

The neurobiological bases of mood disorders remain elusive but both monoamines and neuropeptides may play important roles. The neuropeptide cocaine and amphetamine regulated transcript (CART) was shown to induce anxiety-like behavior in rodents, and mutations in the human CART gene are associated with depression and anxiety. We measured CART-like immunoreactivity (-LI) in genetic rat models of ...

The paper investigates the nonlinear function spaces introduced by Giaquinta, Modica and Souček. It is shown that a function from Cart(Ω,Rm) is approximated by C functions strongly in A(Ω,R) whenever q < p. An example is shown of a function which is in cart(Ω,R) but not in cart(Ω,R).

What’s all the fuss about? The original issue in CHI-WEB was whether to use a shopping cart metaphor when designing e-commerce sites. Some contributors pointed with glee to examples of shopping sleds and wheelbarrows, while others insisted that a cart is a cart is a cart. Don said that we shouldn’t be using any of these things and should just have “lists of items purchased”. Naturally, this lef...