BACKGROUND AND PURPOSE Proton MR spectroscopy has demonstrated reduced levels of N-acetylaspartate (NAA) in normal-appearing occipital and frontal regions of patients with acute nonpenetrating traumatic brain injury (TBI). We studied the relationship of frontoparietal NAA, choline (Cho), and creatine (Cr) to test the hypothesis that reduction in NAA is predictive of cognitive outcome. METHODS...

Recent data suggest that DKA may contribute to cognitive impairment in children with type 1 DM. We measured the NAA/Cr ratio in a teenager during and following 2 separate episodes of DKA without clinically apparent cerebral edema. The NAA/Cr ratio decreased during DKA and improved following recovery. However, the NAA/Cr value was lower after the second episode of DKA (1.76) than after the first...

Two children with acquired immunodeficiency syndrome (AIDS) and progressive encephalopathy underwent MR spectroscopy before and after antiretroviral therapy. Initial MR spectroscopy of the basal ganglia region showed decreased N-acetylaspartate (NAA)/creatine (Cr) and a lactate peak. After therapy, there was improvement in NAA/Cr and an absence of the abnormal lactate peak. We suggest that decr...

The experiment was conducted to study the response of summer onion N2 and Naphthalene Acetic Acid (NAA). consisted two factors. Factor A: 4 levels Nitrogen viz. N0-0kg (control), N1-90kg ha-1, N2-110kg ha-1 N3-130kg B: NAA H0-0ppm, H1- 50ppm, H2-100ppm H3-150ppm. laid out in Randomized Complete Block Design with three replications. Results revealed that terms nitrogen, highest bulb diameter (4....

BACKGROUND AND PURPOSE Subcortical ischemic vascular dementia is associated with cortical hypometabolism and hypoperfusion, and this reduced cortical metabolism or blood flow can be detected with functional imaging such as positron emission tomography. The aim of this study was to characterize, by means of MR imaging and 1H MR spectroscopy, the structural and metabolic brain changes that occur ...

INTRODUCTION To characterize the contents of choline (Cho), creatine (Cr) and N-acetylaspartylglutamate (NAA) in the hippocampus of healthy volunteers, we investigated the contents and their correlationship with age, gender and laterality. MATERIAL AND METHODS Volunteers were grouped into a young, a middle and an old age. The Cho, Cr and NAA contents were determined with proton magnetic reson...

Prior studies have reported hippocampal volume loss, decrease in N-Acetylaspartate (NAA) concentration and increased myo-inositol (mI) concentration in patients with Alzheimer's disease (AD). The purpose of this study was to evaluate hippocampal volumes of AD patients and their correlation with metabolic changes detected by proton spectroscopy (1H MRS) of hippocampal formations and the posterio...

Introduction Neutron activation analysis (NAA) is a nuclear process used for determining the concentrations of elements in a vast amount of materials. NAA relies on excitation by neutrons so that the treated sample emits gamma-rays. It allows the precise identification and quantification of the elements, above all of the trace elements in the sample. NAA has applications in chemistry but also i...

A detailed time study of the incorporation of label from sodium-[lC]acetate, [1C]ethanol, and [2C]glucose into the aspartyl moiety of N -acetylaspartic acid (NAA) was conducted. As expected the specific activity of aspartate increased rapidly with time and peaked within 15 20 min after which it fell sharply: but significant!). that of the aspartyl moiety of NAA rose very slowly even after the s...