نتایج جستجو برای: 01 and well 3w

تعداد نتایج: 16881055  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه رازی - دانشکده علوم 1391

1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...

Journal: :Mechanisms of Development 2009

Introduction: Drawing on the overlap between concepts of wellbeing and motivation, based on motivonia, human motivation is derived by the wellbeing experienced in the past, present, and well-willing (desired future wellbeing). Due to the long-term procedure of learning a foreign language and the necessity of intended effort and maintaining motivated behaviour, this study investigated the effect...

2014
Sagar Rohailla Nadia Clarizia Michel Sourour Wesam Sourour Nitai Gelber Can Wei Jing Li Andrew N. Redington

BACKGROUND Remote ischemic conditioning (RIC), induced by brief periods of limb ischemia has been shown to decrease acute myocardial injury and chronic responses after acute coronary syndromes. While several signaling pathways have been implicated, our understanding of the cardioprotection and its underlying mediators and mechanisms remains incomplete. In this study we examine the effect of RIC...

Introduction: Drawing on the overlap between concepts of wellbeing and motivation, based on motivonia, human motivation is derived by the wellbeing experienced in the past, present, and well-willing (desired future wellbeing). Due to the long-term procedure of learning a foreign language and the necessity of intended effort and maintaining motivated behaviour, this study investigated the effect...

Journal: :Genetics 2014
Alan J Herr Scott R Kennedy Gary M Knowels Eric M Schultz Bradley D Preston

Genetic defects in DNA polymerase accuracy, proofreading, or mismatch repair (MMR) induce mutator phenotypes that accelerate adaptation of microbes and tumor cells. Certain combinations of mutator alleles synergistically increase mutation rates to levels that drive extinction of haploid cells. The maximum tolerated mutation rate of diploid cells is unknown. Here, we define the threshold for rep...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شاهد - دانشکده علوم انسانی 1392

در این تحقیق، ما مدل بهینه سازی پورتفولیو را با استفاده از ارزش در معرض ریسک انجام داده و نشان دادیم که روش بهینه سازی چند-دوره ای در مقایسه با روشهای معمولی بهینه سازی نتایج بهتری را بدست می دهد. ما با استفاده از سناریوهای درختی اقدام به تولید احتمالات وقوع سناریوها نموده و سپس در هر سناریو بهترین و بهینه ترین مورد ممکن را با استفاده از روش ارزش در معرض ریسک احتمالی را انتخاب کرده و اقدام به ر...

2013
Henry A. Erlich Ana Maria Valdes Shana L. McDevitt Birgitte B. Simen Lisbeth A. Blake Kim R. McGowan John A. Todd Stephen S. Rich Janelle A. Noble

The primary associations of the HLA class II genes, HLA-DRB1 and HLA-DQB1, and the class I genes, HLA-A and HLA-B, with type 1 diabetes (T1D) are well established. However, the role of polymorphism at the HLA-DRB3, HLA-DRB4, and HLA-DRB5 loci remains unclear. In two separate studies, one of 500 subjects and 500 control subjects and one of 366 DRB1*03:01-positive samples from selected multiplex ...

Journal: :Rheumatology 2013
Kenichi Shimane Yuta Kochi Akari Suzuki Yukinori Okada Tomonori Ishii Tetsuya Horita Kazuyoshi Saito Akiko Okamoto Norihiro Nishimoto Keiko Myouzen Michiaki Kubo Michito Hirakata Takayuki Sumida Yoshinari Takasaki Ryo Yamada Yusuke Nakamura Naoyuki Kamatani Kazuhiko Yamamoto

Objective. To re-evaluate the roles of HLA-DRB1 alleles in susceptibility to SLE and RA and their effects on autoantibody status in large-scale Japanese cohorts. Methods. A total of 656 SLE, 2410 RA and 911 control subjects, who were all Japanese, were genotyped for HLA-DRB1 alleles using sequence-specific oligonucleotide probes. The association of alleles with disease susceptibility was tested...

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