Worldwide human fertility has been facing a significant decline over recent years. Therefore, attention focused on identifying environmental and lifestyle risk factors that may be contributing to impact reproductive function. The use of alcohol, tobacco certain medications have undergone substantial assessment into their effects fertility. As physicians aim offer the most appropriate recommenda...

Background: Circulating cell-free DNA (cfDNA) is a novel type of biomarker with broad utility in diagnostic medicine, based on the release fragments from dying cells to circulation. We developed an approach for identifying tissue origins cfDNA, using cell-type-specific methylation patterns, massive reference atlas genome-wide methylomes multiple human tissues and cell types. Cancer inflicts dam...