Abstract In an attempt to develop new anti‐inflammatory agents which act by co‐release of carbon monoxide (CO) and a specialized pro‐resolving mediator, we designed conjugates lipoxin A 4 analogue acyloxycyclohexadiene‐Fe(CO) 3 complex as esterase‐triggered CO‐releasing molecule (ET‐CORM). After adjustment the protecting group strategy, two such compounds were successfully prepared total synthe...

Several saffron ecotypes (Mashhad, Torbat-Jam, Torbat-Haydarieh, Gonabad, Birjand, Ghaen) were evaluated in Urmia for stigma yield and yield components using different maternal corm weights(6, 8, 10, 12 g) in 2013 cropping year. The experiment was arranged as factorial based on randomized complete block design. Analysis of variance showed that there were significant differences among saffron ec...

We report a new R package implementing the clustering of regression models (CORM) method for clustering genes using gene expression data and provide data examples illustrating each clustering function in the package. The CORM package is freely available at CRAN from http://cran.r-project.org.

In the 1990’s, the World Agroforestry Centre (ICRAF) initiated a domestication programme of indigenous fruit trees (IFTs) in Southern Africa to increase farmhousehold income through farmer-led tree planting and thus conserve bio-diversity. From the farmer's point of view planting domesticated IFTs is an investment under uncertainty and irreversibility. As timing of planting is flexible, real op...

The aim of the present study was to investigate whether carbon monoxide (CO) induces changes in ion transport across the distal colon of rats and to study the mechanisms involved. In Ussing chamber experiments, tricarbonyldichlororuthenium(II) dimer (CORM-2), a CO donor, evoked a concentration-dependent increase in short-circuit current (I(sc)). A maximal response was achieved at a concentratio...

The development of carbon monoxide-releasing molecules (CO-RMs) in recent years helped to shed more light on the diverse range of anti-inflammatory and cytoprotective activities of CO gas. In this study, we examined the effect of a ruthenium-based water-soluble CO carrier (CORM-3) on lipopolysaccharide (LPS)and interferon(INF)-induced inflammatory responses in BV-2 microglial cells and explored...

in other to evaluate grain yield, rate and effective grain filling period of four barley (hordeum vulgaris l.) cultivars in different planting dates, a factorial experiment based on a randomized complete block design was conducted in the islamic azad university of ardabil research station in 2009. the treatments applied were: three levels of different planting dates (september, 23; october, 16 ...