نتایج جستجو برای: 2 cell

تعداد نتایج: 3839288  

Journal: :journal of sciences islamic republic of iran 0
f. karami-tehrani cancer research laboratory, department of clinical biochemistry, school of medical sciences, university of tarbiat modarres, tehran, islamic republic of iran

the purpose of the present study is to investigate the cytotoxicity/apoptotic effect of 2-chloro-2′-deoxyadenosine, cladribine, (2-cda) in the human breast cancer cell line, mda-mb468 (estrogen receptor negative, er−). mtt [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h tetrazolium bromide] assay, annexin v-fluorescein/pi and hoechst 33258 staining were used to detect cytotoxicity and cell apopto...

Journal: :razavi international journal of medicine 0
federico ferro orthopaedic trauma institute, san francisco general hospital, university of california, san francisco, usa; orthopaedic trauma institute, san francisco general hospital, university of california, 2550 23rd street, san francisco, usa. tel: +1-4152065362 chelsea shields baheney orthopaedic trauma institute, san francisco general hospital, university of california, san francisco, usa renza spelat school of veterinary medicine, university of california, davis, usa

conclusions our underlying hypothesis is that recapitulating the three-dimensional early embryonic structure, in order to reproduce better in vitro the three-dimensional morphogenetic-like re-arrangements, would improve cells differentiation, when in vivo transplanted; moreover, it could be used as a simplified cancer disease model and reliable drug evaluation method as well. results the proces...

Journal: :gene, cell and tissue 0
zahra farzaneh taban department of biology, basic sciences faculty, islamic azad university of hamadan, hamadan, iran shiva khatibi department of biology, basic sciences faculty, islamic azad university of hamadan, hamadan, iran raheleh halabian applied microbiology research center, baqiyatallah university of medical sciences, tehran, ir iran amaneh mohammadi roushandeh endometrium and endometriosis research center, hamadan university of medical sciences, hamadan, ir iran; endometrium and endometriosis research center, hamadan university of medical sciences, hamadan, ir iran

conclusions our data suggest that preconditioning with 5 μm h2o2 + 0.5% fbs and 10 μm h2o2 + 5% fbs improved cell proliferation and viability. however, the mechanisms related to protective properties of preconditioning and using this strategy in stem cell therapy requires more research. background mesenchymal stem cells (mscs) survival decreased following in vivo injection and its application h...

Journal: :journal of reproduction and infertility 0

background: due to increasing clinical demand for adipose tissue, a suitable cell for reconstructive adipose tissue constructs is needed. in this study, we investigated the ability of human endometrial-derived stem cells (enscs) as a new source of mesenchymal stem cells to differentiate into adipocytes. enscs are the abundant and easy available source with no immunological response, for cell re...

Journal: :iranian journal of immunology 0
yang li department of orthopaedics lu zhang department of maternity, first affiliated hospital, dalian medical university, dalian, liaoning province, china shouyu wang department of orthopaedics peng shi department of orthopaedics wei qu department of orthopaedics

background: fusion of dendritic cells (dcs) with melanoma cells could reinforce the antigenicity of tumors as a strategy for the treatment of malignant melanoma. however, the insufficient quantity of dcs and the low fusion efficiency limits the development of such approach. objective: to define the dosage of the stimulating factors as well as the induction condition for the optimal dcs preparat...

Journal: :international journal of reproductive biomedicine 0
ying zhang hong cao zheng yu hai-ying peng chang-jun zhang

background: endometriosis is a complex estrogen-dependent disease that is defined as the presence of endometrial gland and stroma outside the uterine cavity. although the exact mechanism for the development of endometriosis remains unclear, there is a large body of research data and circumstantial evidence that suggests a crucial role of estrogen in the establishment and maintenance of this dis...

Background and purpose: In 2019, the world has witnessed the emergence of a virus that caused acute respiratory distress syndrome in human with high mortality rates (approximately 3.7%). So far, no effective treatment has been proven against COVID-19. This study aimed at designing a multi-epitope vaccine combining several T-cell and B-cell epitopes of the SARS-CoV-2. Materials and methods: Bas...

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