BACKGROUND/AIMS Chronic hepatitis B infection is a common cause of secondary membranous nephropathy (MN) in endemic areas. Lamivudine treatment improves renal outcome in patients with hepatitis B virus-associated MN (HBV-MN), but prolonged use leads to the emergence of lamivudine-resistant variants. We describe our experience treating lamivudine-resistant and other strains of HBV-MN with new an...

Novel half-sandwich 18ē and 16ē arene ruthenium iminophosphonamide complexes [(η6-C6Me6)RuCl{(R'N)2PR2}] (3a-c) and [(η6-C6Me6)Ru{(R'N)2PR2}]+(X-) (4a-c) (a, R = Ph, R' = p-Tol; b, R = Et, R' = p-Tol; c, R = Ph, R' = Me. X = BF4, PF6 or BArF4) were synthesized. The elongated Ru-Cl bond in the 18ē complexes is shown to dissociate even in apolar solvents to form the corresponding 16ē cations, whi...

background: benzene is one of the important occupational pollutants. there are some reports about the leukemogenic effects related to low-level exposure to benzene. objective: to study the frequency of micronucleus (mn), nucleoplasmic bridge (nb), and nuclear budding (nbud) in the peripheral blood lymphocytes of petrochemical workers with low level exposure to benzene. methods: we enrolled 50 w...

Let A ∈ Mn(C ). We give a rank characterization of the semidefiniteness of Hermitian A in two ways. We show that A is semidefinite if and only if rank[X∗AX] = rank[AX], for all X ∈ Mn(C ), and we show that A is semidefinite if and only if rank[X∗AX] = rank[AXX∗], for all X ∈ Mn(C ). We show that if A has semidefinite Hermitian part and A has positive semidefinite Hermitian part then A satisfies...

First-principles calculations were performed to study the structural, electronic, and magnetic properties of bcc Fe with C impurities alloyed with 2, 3, and 6 at.% of Mn. Our results reveal that both manganese concentration and carbon location with respect to Mn affect the Fe-Mn magnetic interaction. With an increase in Mn concentration in bcc Fe-Mn alloy, the local magnetic moment of manganese...

Membranous nephropathy (MN) most commonly is idiopathic, but secondary causes are common in children and in older adults. The most common secondary causes of MN in industrialized countries include malignancy and systemic lupus erythematosis. Infectious causes (hepatitis B, quartan malaria, schistosomiasis) remain the most common etiologies in endemic areas. In this article we describe the clini...

Previous studies have demonstrated that the divalent cation manganese (Mn) causes PC12 cells to form neurites in the absence of NGF. Since divalent cations modulate the binding affinity and specificity of integrins, and integrin function affects neurite outgrowth, we tested the hypothesis that Mn induces neurite outgrowth through an integrin-dependent signaling pathway. Our studies support this...

Pressure effects on the stability of magnetic phases in La(1.4)Sr(1.6)Mn(2)O(7) have been studied using magnetization measurements and neutron diffraction. At ambient conditions this material is a quasi-two-dimensional ferromagnet. On cooling it becomes ordered three dimensionally: at 90 K La(1.4)Sr(1.6)Mn(2)O(7) it becomes an antiferromagnet, and at 65 K it undergoes a transition into a ferrom...