In a study that examined associations between single nucleotide polymorphism (SNP) loci within the promoter of the PRTN3 gene and the autoimmune disease Wegener’s granulomatosis (WG), we implemented a self-administered pilot survey that captured participants’ demographic data, family relationships, incidence of autoimmune disease among family members, and attitudes about DNA collection. We next...

The management of pressure sores in community settings, poses a clinical problem which challenges the patient’s toler­ ance and the clinician’s diligence and ingenuity. Pressure sores can be painful, lead to infection and are associated with con­ siderable morbidity and increased mortality (Patterson & Bennett, 1995:919; Bale, Banks, Hagelstein & Harding, 1998:65). Treatment costs of these woun...

AND MANAGEMENT IN MODELING AND COMPUTATION H.T. Banks Center for Research in Scienti c Computation Box 8205 North Carolina State University Raleigh, NC 27695-8205 Fax: 919 515-1636 email: [email protected] ABSTRACT We discuss questions related to uncertainty in scienti c computations for mathematical models. A computationally tractable probabilistic framework to treat uncertainty in the esti...

Running title: Eye-centered auditory signals in monkey SC 4 5 Authors and affiliations: Jungah Lee and Jennifer M. Groh 6 Center for Cognitive Neuroscience, Department of Psychology and Neuroscience, Department of 7 Neurobiology, Duke University 8 Email: [email protected], [email protected] 9 10 Corresponding author and address: 11 Jungah Lee 12 LSRC Rm B245 Box 90999 Duke University Durham, NC...

China’s demand for air transportation is widely expected to increase further, and the Chinese aviation community are now also designing their own commercial aircraft, the COMAC C-919. Consequently, the interactions in the air between the West and China are anticipated to become far more extensive and dynamic. However, due to the multi-faceted nature of Chinese culture, it is sometimes difficult...

Novan Therapeutics | 4222 Emperor Boulevard, Suite 470, Durham, North Carolina 27703 | (919) 485-8080 | www.novantherapeutics.com Introduction Novan Therapeutics, a clinical-stage drugdevelopment company, has developed drug candidate SB204, which releases nitric oxide when applied topically to the skin. Based on results from animal studies, locally available nitric oxide may inhibit skin steroi...

Results: If no treatment were given, of the 103 582 individuals developing neovascular AMD for which ranibizumab would be indicated and available, 16 268 would become legally blind in 2 years. Monthly ranibizumab would reduce the incidence of legal blindness in 2 years by 72% (95% confidence interval [CI], 70% to 74%) to 4484 individuals. If no treatment were given, 34 702 would become visually...