نتایج جستجو برای: ad syndrome
تعداد نتایج: 703903 فیلتر نتایج به سال:
سلولهای بنیادی مزانشیمی (mscs) گروهی از سلولهای بنیادی بالغین هستند که بصورت طبیعی در بدن وجود داشته و حضور این سلولها در بافت های مختلف گزارش شده است. امروزه بدلیل قابلیت ذاتی این سلولها در تمایز به رده های مختلف، توجه زیادی را در زمینه های سلول درمانی و ژن درمانی به خود معطوف کرده¬اند. مغز استخوان و بافت چربی بعنوان دو منبع عمده این سلولها هستند. با وجود اینکه مغز استخوان (bm) بعنوان اولین من...
Mycosis fungoides (MF) and Sézary syndrome (SS) are classical types of cutaneous T-cell lymphoma (CTCL). MF is the most common type CTCL, which characterized by malignant proliferation neoplastic CD4+ T cells with epidermotropism in skin. SS an aggressive leukemic CTCL a triad erythroderma, lymphadenopathy involvement. Squamous cell carcinoma antigen (SCCA) was originally isolated as tumor-spec...
در این تحقیق، کلیه های موش سوری سلول زدایی شده و به عنوان یک داربست سه بعدی طبیعی برای بررسی اثر آن بر رفتار سلول های بنیادی مزانشیمی مشتق از بافت چربی انسانی (ad-mscs) در شرایط in vitro مورد استفاده قرار گرفتند. روش کار: برای آماده سازی داربست های طبیعی، تیمار های فیزیکی و شیمیایی سلول زدایی بر کلیه ی موش نر اعمال شدند. پس از تیمار فیزیکی که شامل انجماد آهسته و انجماد و ذوب سریع بود، کلیه ها ...
BACKGROUND Heritability of Alzheimer's disease (AD) is estimated at 74% and genetic contributors have been widely sought. The ε4 allele of apolipoprotein E (APOE) remains the strongest common risk factor for AD, with numerous other common variants contributing only modest risk for disease. Variability in clinical presentation of AD, which is typically amnestic (AmnAD) but can less commonly invo...
Around 50% of patients with Alzheimer’s disease (AD) may experience psychotic symptoms after onset, resulting in a subtype AD known as psychosis (AD + P). This is characterized by more rapid cognitive decline compared to without psychosis. Therefore, there great need identify risk factors for the development P and explore potential treatment options. In this study, we enhanced our deep learning...
It is becoming apparent that with an aging population comes an increase in the incidence of mental impairment. In death certificates of people over 75 years of age, the number listed as having dementia has increased by a factor of 20 in the last 15 years (Forbes, Lessard, & Gentleman, 1995, appearing in the present issue). Most of this increase is probably the result of heightened diagnostic se...
BACKGROUND Several peptides, named adipokines, are produced by the adipose tissue. Among those, adiponectin (AD) is the most abundant. AD promotes peripheral insulin sensitivity, inhibits liver gluconeogenesis and displays anti-atherogenic and anti-inflammatory properties. Lower levels of AD are related to a higher risk of myocardial infarction and a worse prognosis in patients with coronary ar...
PURPOSE Myopia, or nearsightedness, is a visual disorder of high and growing prevalence in the United States and in other countries. Pathologic high myopia, or myopia of </=-6.00 D, predisposes individuals to retinal detachment, macular degeneration, cataracts, and glaucoma. Autosomal dominant (AD) nonsyndromic high-grade myopia has been mapped to loci on 18p11.31, 12q21-q23, 17q21-q23, and 7q3...
Although we stimulate enterocytic proliferation to ameliorate short gut syndrome or mucosal atrophy, less effort has been directed at enterocytic differentiation. Schlafen 3 (Slfn3) is a poorly understood protein induced during IEC-6 enterocytic differentiation. We hypothesized that exogenous manipulation of Slfn3 would regulate enterocytic differentiation in vivo. Adenoviral vector coding for ...
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