نتایج جستجو برای: advanced gastric cancer
تعداد نتایج: 1168868 فیلتر نتایج به سال:
cancer has been always in a great attention in the field of molecular biology. by applying large-scale tools such as advanced proteomics, cancer diagnosis and treatment have been improved greatly since. cancers of esophagus, gastric, and colon accounted for major health problem globally. biomarker panel could bring out the accuracy for cancer evaluation tests as it can suggest a group of can...
Background and purpose: Gastric cancer has been considered as the second lethal cancer throughout the world and the incidence of this cancer in Ïran is 25 in 10000 people per year. Ïnterleukin-11 (ÏL-11), a member of ÏL-6 family, may play some role in developing gastric cancer via activation of the JÂK/STÂT signaling pathway. Ïn this study, the level of ÏL-11 gene expression was determined in g...
BACKGROUND The treatment of patients with advanced gastric cancer remains a most challenging task in the clinical practice. Recently, targeted therapies have significantly impacted the treatment strategy for many common malignancies. The use of trastuzumab, a monoclonal antibody against human epidermal growth factor receptor 2 (HER2; also known as ERBB2), plus chemotherapy proved to improve med...
BACKGROUND Our study aimed to investigate the clinicopathological feature and prognostic role of miR-509-3-5P in gastric cancer, to determine the invasive and metastatic role of miR-509-3-5P in vitro and in vivo and to explore the molecular mechanism between miR-509-3-5P and PODXL. RESULTS Strikingly lower miR-509-3-5P expression was detected in gastric cancer tissues with advanced tumor stag...
Objective(s):MiRNAs have been proposed to be key regulators of tumorigenesis, progression and metastasis. However, their effect and prognostic value in gastric cancer is still poorly known. Materials and Methods: Gastric cancer cell lines were cultured. Tissue samples obtained from 36 gastric cancer patients were used for quantitative real-time PCR (qRT-PCR) analysis. The tissue microarrays (T...
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