BACKGROUND Elderly patients with end-stage renal disease and severe extra-renal comorbidity have a poor prognosis on renal replacement therapy (RRT) and may opt to be managed conservatively (CM). Information on the survival of patients on this mode of therapy is limited. METHODS We studied survival in a large cohort of CM patients in comparison to patients who received RRT. RESULTS Over an ...

BACKGROUND Acute renal failure (ARF) occurs in up to 10% of critically ill patients, with significant associated morbidity and mortality. The optimal mode of renal replacement therapy (RRT) remains controversial. This retrospective study compared continuous renal replacement therapy (CRRT) and intermittent hemodialysis (IHD) for RRT in terms of intensive care unit (ICU) and hospital mortality, ...

OBJECTIVES To study the epidemiology of chronic kidney disease (CKD) in children, and to look for risk factors to predict renal replacement therapy (RRT) and mortality. METHODS This is a retrospective cohort study conducted at King Abdulaziz University Hospital, Jeddah, Saudi Arabia between 2006 and 2014, where the files of 1,000 children with CKD were reviewed. We determined the effect of co...

Optimal path planning refers to find the collision free, shortest, and smooth route between start and goal positions. This task is essential in many robotic applications such as autonomous car, surveillance operations, agricultural robots, planetary and space exploration missions. Rapidly-exploring Random Tree Star (RRT*) is a renowned sampling based planning approach. It has gained immense pop...

INTRODUCTION In this cohort study, we explored the relationship between fluid balance, intradialytic hypotension and outcomes in critically ill patients with acute kidney injury (AKI) who received renal replacement therapy (RRT). METHODS We analysed prospectively collected registry data on patients older than 16 years who received RRT for at least two days in an intensive care unit at two uni...

BACKGROUND Perioperative complication of end-organ injury including acute kidney injury (AKI) is a frequent and severe problem for patients undergoing left ventricular assist device (LVAD) implantation. This study evaluated an emerging AKI biomarker, plasma neutrophil gelatinase-associated lipocalin (NGAL), in a LVAD implantation cohort. METHODS AND RESULTS Of 31 LVAD implantation patients en...

BACKGROUND Radiocontrast-induced nephropathy (RCIN) is an important cause of acute kidney injury, increasing in-hospital and long-term mortality. It is controversial whether prophylactic renal replacement therapy (RRT) may reduce a patient's risk of RCIN when compared with standard medical therapy (SMT). METHODS We searched through PubMed and bibliographies of retrieved articles. Published st...

BACKGROUND In a retrospective case-note and computer database analysis we assessed the outcome of very elderly patients (> or = 75 years old) with end-stage renal disease (ESRD) on renal replacement therapy (RRT). METHODS Fifty-eight individuals aged 75 or over (group 1) commenced RRT between 1 January 1991 and 31 December 1995. Comparisons were made with other patients commencing RRT who wer...

Patients with CRF usually progress through different stages before they reach ESRD and require special medical, social and psychological care and support during the pre-ESRD and following renal replacement therapy (RRT). Early referral of patients with CRF has the advantage of receiving adequate management and regular followup, with significant reduction in cardiovascular morbidity and mortalit...

Diabetic nephropathy is now the most common renal disease leading to renal replacement therapy in developed countries. Within the UK, the number of DN patients accepted for RRT rose steadily in the 1990s especially in the African–Caribbean and South Asian populations. This may be related to the increased prevalence of Type 2 diabetes in the general population, the ageing population and the libe...