One of the superficial problems of public health is mycotic inflection that its incidence is not correctly known. The most important disease of them is dermatophytosis that comes through by dermatophytes as the major group of keratinophilic fungi. Honey is bee product that has been used as a medicine since ancient times in many cultures, and is still used in folk medicine. This study was design...

The structural requirements for the inhibitor activity of various furan carboxanilide derivatives against succinate dehydrogenase complex (SDC) activity in mitochondria of either wild or mutant strains of Ustilago maydis were investigated with the aid of Hansch QSAR analysis. It has been found that the inhibitor activity against both types of enzymes is best related to the ??? or ??M of th...

A synthesis of 2-Isonicotinyl 3, 5-diaryl -2H-(3-tetrazolium) chloride (5) was performed starting from isonicotinic hydrazide (1). The treatment of 1 with various substituted aromatic aldehydes afforded the corresponding Schiff’s bases 3. The Schiff’s bases are converted into a series of aryl formazan via diazocoupling which underwent cyclization in the presence of H2O2 and KMnO4 to give substi...

Background & Aim: The aim of this study was to assess the antifungal effect of the watercress extract on the growth of Fusarium solani, the causal agent of potato dry rot. Experimental:  This research was done in a completely randomized design with three concentrations and four replicates on potato dextrose agar (PDA) culture medium. Results: Results of this study indicated that all ...

BACKGROUND Nowadays Candida albicans has become resistant to the toxic and expensive commercial anti-Candida drugs. Therefore, investigation for new anti-fungal agents is necessary. OBJECTIVES The purpose of this survey was to investigate the in vitro anti-Candida activity of the hydroalcoholic extracts of Heracleum persicum fruit. MATERIALS AND METHODS The plant ingredients were extracted ...

I was diagnosed several years ago with Meniere's disease. In 2009, it had progressed to the point where I was unable to function. I was ready to file for disability until serendipity led me to be treated with nystatin and systemic anti-fungal drugs. The anti-fungal drugs have brought about almost complete relief from my Meniere's and Migraine symptoms (documented with hearing tests). I have als...

Zygomycosis is an opportunistic fungal infection with a high mortality rate. It is known to cause invasive disease in immunocompromised hosts but it may produce only cutaneous/ subcutaneous infections in immunocompetent hosts. Treatment is difficult due to its fulminant course and lack of effective anti-fungal drugs. Here, we report a rare case of subcutaneous zygomycosis caused by Mucor hiemal...

Filamentous fungi are important due to their high enzymes production potential. Many enzymes produced by fungi have related to biotechnological applications in several industrial sectors. The purpose of this study was to collect and isolate Penicillium and Aspergillus species from different sources and examined for their ability to produce cellulase and amylase. Ten fungal isolates of genera, A...

objective: the present study was undertaken to evaluate the possible analgesic, neuropharmacological, anti-diarrheal, and cytotoxic activities of the ethanol extract of leaves of solanum sisymbriifolium lam. (family: solanaceae). materials and methods: the analgesic activity was measured by acetic acid-induced writhing inhibition test. the neuropharmacological activities were evaluated using ho...

Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. In line with these developments the synthesis of N-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4H-1...