Classical studies indicate that the contribution of kidneys to hypertension is almost exclusively related to the association between mean arterial pressure (MAP) and vascular resistance. Recent reports including estimates of glomerular filtration rate (GFR) have shown that pulse pressure (PP) and pulse wave velocity, 2 major indices of arterial stiffness, now emerge as significant predictors of...

In 1948, Hellems, Haynes, Dexter, and Kinney, using venous and arterial catheterization in dogs obtained pressure recordings from both sides of the pulmonary capillary bed. The method consisted in wedging the tip of a cardiac catheter into a small branch of the pulmonary artery and of the pulmonary vein respectively, and recording the mean blood pressures in the obstructed vascular bed distal t...

Risk factors for cardiovascular disease mediate their effects by altering the structure, properties, and function of wall and endothelial components of arterial blood vessels.1 The ability to detect and monitor change in the physical properties of arteries, representative of the cumulative and integrated influence of hemodynamic, metabolic, and inflammatory stimuli in impairing arterial wall in...

OBJECTIVE We have recently shown that mean pulse pressure is higher in patients with transient myocardial ischemia. Pulse pressure elevation might be an important consequence of increased arterial stiffness. The aim of this study was to prove if arterial stiffness is changed in patients with transient myocardial ischemia who bear a high cardiovascular risk. Additionally we investigated whether ...

BACKGROUND The association between hypothyroidism and increased vascular resistance, arterial wall thickening and endothelial dysfunction is well recognized. The aim of the present study was to examine if hypothyroid subjects have increased arterial stiffness, a risk factor for cardiovascular morbidity and mortality. METHODS Sixty-five subjects (59 females and 6 males) with normal thyroid fun...

Simultaneous recordings of reflected ultrasound from the anterior mitral leaflet and left ventricular outflow, the ECG, the phonocardiogram, and a recording of the carotid artery pulse were obtained in six patients with hypertrophic obstructive cardiomyopathy. Abnormal sharp systolic anterior movement (SAM) of the mitral leaflet was observed. This movement began with the onset of ventricular ej...

Background and Objectives: Suction is a necessary and common method which aids in the release of secretion from the respiratory system for the patients who have undergone mechanical ventilation. One of the most common complications of suction is hypoxemia which causes dysrhythmia and death. The purpose of this study was to determine the effects of open and closed-endotracheal suction on cardiov...

Pulse wave analysis is widely used to monitor cardiovascular diseases. Our previous studies have shown the arterial pressure wave drives the blood into tissue. The output from the heart, which generates the harmonics of the heartbeat, and the matching condition of the heart with the arterial system are mutually influenced to generate the harmonic spectrum of pulse wave. Here we review experimen...